Leica Microscope Magnifier M205 FA User Manual

Leica M165 FC  
Leica M205 FA  
User Manual  
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Important Safety Notes  
User Manual  
You can combine individual system articles  
with articles from external suppliers (e.g. cold  
light sources, etc.). Please read the user manual  
and the safety requirements of the supplier.  
Special manuals  
Special manuals are provided for a number of  
accessories:  
The individual modules of the Leica M stereo-  
microscopy series include an interactive  
CD-ROM with all relevant user manuals in  
20 other languages. Keep it in a safe place,  
and readily accessible to the user. User manu-  
als and updates are also available for you  
to download and print from our web site at  
www.stereomicroscopy.com.  
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User Manual M2-216-1 for lamp housing  
Before installing, operating or using the instru-  
ments, read the user manuals listed above.  
In particular, please observe all safety instruc-  
tions.  
with high-pressure mercury burner.  
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User Manual for ebq 100 isolated supply  
unit for 100W high-pressure mercury  
burners.  
This User Manual describes the special func-  
tions of the individual modules of the Leica M  
stereomicroscopy series and contains impor-  
tant instructions for their operational safety,  
maintenance, and accessories.  
To maintain the unit in its original condition  
and to ensure safe operation, the user must  
follow the instructions and warnings contained  
in these user manuals.  
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User Manual M2-267-1 for the motorized  
focus system.  
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User Manual M2-166-2 for FluoCombi III™.  
The "Safety concept" booklet contains addi-  
tional safety information regarding the service  
work, requirements and the handling of the  
stereomicroscope, accessories and electrical  
accessories as well as general safety instruc-  
tions.  
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3
 
Symbols Used  
Warning of a danger  
Danger due to hot surface  
This symbol warns against touching  
accessible hot surfaces, e.g. those of  
light bulbs.  
This symbol indicates especially impor-  
tant information that must be read and  
complied with.  
Failure to comply can cause the following:  
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Hazards to personnel  
Functional disturbances or damaged instru-  
ments  
Important information  
This symbol indicates additional infor-  
mation or explanations that intend to  
provide clarity.  
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Warning of hazardous electrical voltage  
This symbol indicates especially impor-  
tant information that is mandatory to  
read and observe.  
Explanatory notes  
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This symbol within the text stands for addi-  
tional information and explanations.  
Failure to comply can cause the following:  
Figures  
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Hazards to personnel  
Functional disturbances or damaged instru-  
ments  
(1) Numbers in parentheses within the  
descriptions relate to the figures and the  
items within those figures.  
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Safety Instructions  
Description  
are outside of the scope of this manual.  
Responsibilities of person in charge of  
instrument  
The individual modules fulfill the highest  
requirements for observation and documenta-  
tion of Leica stereomicroscopes of the M series.  
Unauthorized alterations to the instrument or  
noncompliant use shall void all rights to any  
warranty claims.  
Refer to "Safety Concept" booklet  
Ensure that:  
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Intended use  
The  
M
series stereomicroscopes and  
Refer to "Safety Concept" booklet  
Place of use  
accessories are operated, maintained and  
repaired by authorized and trained person-  
nel only.  
Refer to "Safety Concept" booklet  
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Non-intended use  
Refer to "Safety Concept" booklet  
Electrical components must be placed at  
least 10 cm away from the wall and from  
flammable substances.  
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All operators have read, understood and  
observe this User Manual, and particularly  
the safety instructions.  
Never use M series microscopes or their compo-  
nents for surgical procedures (e.g. on the eye)  
unless they are specifically intended for that  
purpose.  
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Avoid large temperature fluctuations,  
direct sunlight and vibrations. These condi-  
tions can distort measurements and micro-  
graphic images.  
The instruments and accessories described in  
this operating manual have been tested for  
safety and potential hazards. The responsible  
Leica affiliate must be consulted whenever  
the instrument is altered, modified or used in  
conjunction with non-Leica components that  
In warm and warm-damp climatic zones,  
the individual components require special  
care in order to prevent the build-up of  
fungus.  
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Safety Instructions (cont'd.)  
Repairs, service work  
Integration in third-party products  
Refer to "Safety Concept" booklet  
this reason, appropriate measures for reduction  
of the workload must be taken:  
Refer to "Safety Concept" booklet  
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Only original Leica Microsystems spare  
parts may be used.  
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Optimal arrangement of workplace, work  
assignments and work flow (changing tasks  
frequently).  
Disposal  
Refer to "Safety Concept" booklet  
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Before opening the instruments, switch off  
the power and unplug the power cable.  
Thorough training of the personnel, giving  
consideration to ergonomic and organiza-  
tional aspects.  
Legal requirements  
Touching the live circuit can cause  
injury.  
Refer to "Safety Concept" booklet  
The ergonomic design and construction  
of the Leica M stereomicroscopy series are  
intended to reduce the exertion of the user  
to a minimum.  
EC Declaration of Conformity  
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Refer to "Safety Concept" booklet  
Transport  
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Use the original packaging for shipping or  
transporting the individual modules of the  
Leica M stereomicroscopy series and the  
accessory components.  
Health risks  
Workplaces with stereomicroscopes  
facilitate and improve the viewing task,  
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but they also impose high demands on the eyes  
and holding muscles of the user. Depending on  
the duration of uninterrupted work, asthenopia  
and musculoskeletal problems may occur. For  
In order to prevent damage from vibrations,  
disassemble all moving parts that (accord-  
ing to the user manual) can be assembled  
and disassembled by the customer and  
pack them separately.  
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6
Safety Instructions (cont'd.)  
Direct contact with eyepieces is a poten-  
tial transmission method for bacterial  
Light sources: Safety regulations  
Protective measures of the manufacturer:  
Warning  
UV radiation could damage the eyes.  
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and viral infections of the eye.  
UV protection screen in front of the speci-  
men plane prevents the user from looking  
directly into the UV rays.  
Therefore:  
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The risk can be kept to a minimum by using  
personal eyepieces for each individual or  
detachable eyecups.  
Never look into the light spot on the speci-  
men plane without a UV protection screen.  
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Dummy filter carriers in the free positions  
of the rapid filter changer prevent direct UV  
radiation from reaching the eyes.  
Never look into the eyepieces if no excita-  
tion filter is in the beam path.  
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UV filters are installed in the observation  
beam paths to protect the eyes.  
Fill empty filter positions with dummy filter  
carriers (e.g. M165 FC).  
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The stray-light protection on the lamp  
housing prevents irradiation of the hands.  
Do not select a white, strongly reflective  
background for the specimen.  
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Safety Instructions (cont'd.)  
Supply unit  
Always unplug the supply unit from the power  
supply:  
Lamp housing  
Never open the lamp housing while the  
lamp is switched on. Risk of explosion,  
UV exposure, blinding!  
Mercury lamp  
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Follow the user manual and safety instruc-  
tions provided by the lamp manufacturer,  
and, in particular, the section on how to  
proceed if a lamp breaks and releases  
mercury.  
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When installing and disassembling the  
lamp housing  
Before opening the lamp housing, allow  
it to cool off for at least 15 minutes.  
Danger of explosion!  
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Before opening the lamp housing  
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For transport, remove the mercury lamp,  
transport it in its original packaging and  
protect moving parts in the lamp housing  
using the transport anchors.  
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When replacing the high-pressure mercury  
lamp and other parts, such as the heat-  
absorbing filter or the collector  
Never cover the air duct on the lamp  
housing. Danger of fire!  
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During maintenance work on the supply  
When it has reached the end of its rated life  
(follow the manufacturer's specifications  
and the minute meter on the supply unit).  
unit  
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To minimize the risk of explosion, replace a  
discolored mercury lamp promptly.  
Leica Microsystems assumes no liability  
for damage caused by exploding, incor-  
rectly installed or improperly used mercury  
lamps.  
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8
Contents  
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9
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The Leica M Series  
for Fluorescence  
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12  
 
Congratulations!  
Congratulations on obtaining your new Leica M series stereomicroscope.  
We are convinced it will exceed your expectations, as never before have  
we applied our decades of experience in the areas of optics, mechanical  
engineering and ergonomics in such an uncompromising manner.  
Though the reliability and robustness of Leica stereomicroscopes is  
legendary, like any high-tech product, the Leica M series requires a certain  
degree of care and attention. Therefore, we recommend that you read  
this manual. It contains all the information you need regarding operation,  
safety and maintenance. Simply observing a few guidelines will ensure  
that even after years of intensive use, your stereomicroscope will continue  
to work as smoothly and reliably as on the very first day.  
The Leica M series embodies all the qualities you associate with the name  
Leica Microsystems: excellent objectives, high-quality engineering, and  
reliability. Furthermore, the modular design ensures that the M series  
adapts perfectly to your needs—no matter which accessories you require  
for your tasks.  
We wish you the best of success in your work—after all, you are now  
equipped with the best tool!  
The entire imaging system, including the zoom, objective and ErgoTube®,  
is apochromatically corrected with much technological effort. Contrast,  
sharpness, richness in detail, resolution, image and color fidelity are opti-  
mum. Inaddition, thepatentedilluminationbeampathguaranteesatevery  
zoomlevelthatlightutilizationisatamaximumandthatfluorescenceimages  
are intensely luminous on a jet black background.  
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13  
 
A Step Towards Infinity  
Ever since their introduction by Horatio S.  
Greenough, stereomicroscopes have worked  
according to the optical principles based  
primarily on Ernst Abbe's research. For over a  
century, ingenious optics designers and engi-  
neers have worked to push magnification, reso-  
lution and image fidelity to the limit permitted  
by optics.  
Limits are made to be broken  
The Leica M205 FA is the world's first fluores-  
cence stereomicroscope with a zoom range  
of 20.5:1. This accomplishment, however, was  
not enough for Leica's engineers. With the new  
FusionOptic™ in the Leica M205 FA, they have  
succeeded in going yet another step beyond  
previous limits. In addition to the increase in  
magnification, the resolution, too, has been  
increased to up to 1050 lp / mm, which corre-  
sponds to a resolved structure size of 472 nm.  
In doing so, they have always been constrained  
by the interrelation between three factors: the  
higher a microscope's resolution, the lower the  
available working distance. If one increases the  
distance of the optical axes, the three-dimen-  
sional image seen by the observer becomes  
distorted—a sphere becomes an ellipse, a flat  
surface curves towards the observer.  
Of course, this increase in performance benefits  
your everyday work. Set up your specimens on  
the microscope table with comfortable freedom  
of movement and discover details in stereomi-  
croscopy that you could never see before.  
* Leica M205 FA with 1.0× planapochromat and 10× eyepieces  
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14  
 
The Electronics: Comfort, Convenience and Safety for Your Experiments  
Never before have electronics been used as  
extensively in a Leica series as in the new M  
series lineup. Optics carrier, stand, base and  
illuminator are all connected using electrical  
contacts—which provides a number of advan-  
tages.  
Reliability for your experiments  
diaphragm and more and transmits the infor-  
mation to the Leica LAS software. Thus you  
always know the conditions under which an  
image was acquired.  
Exact reproducibility of results is an increas-  
ingly common demand, particularly in research  
and development. The continuous encoding  
captures parameters such as the magnifica-  
tion, the illumination, the position of the iris  
Fewer cables  
A large part of the cables have been routed in  
the interior of the column. Data are also trans-  
ferred via the interface between the column,  
the optics carrier and the carrier. The direct  
result is that you need fewer cables—this not  
only makes your workstation neater and more  
comfortable, it even makes it appear larger.  
Contacts not only transmit data, but also supply  
the power.  
Leica Application Suite (LAS) evaluates the  
transmitted data and can restore the test situa-  
tion later.  
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15  
 
The Modular Design: Everything is Relative  
The Leica M series provides maximum flexibil-  
ity in choosing equipment, thanks primarily to  
the modular configuration and the compatibil-  
ity that Leica has painstakingly maintained for  
decades. The optics carriers, eyepieces, bases  
and more can be combined in any way you  
choose, allowing you to create the microscope  
that best suits your needs.  
Despite this, you will notice that the controls  
Have a special request? Let us know!  
Leica Microsystems enjoys an exceptional repu-  
tation when it comes to devising customer-  
specific solutions. If you have a special request  
that cannot be met with standard parts, contact  
your Leica consultant. We have a solution for  
every problem.  
and individual components do not differ signif-  
icantly. Whichever configuration you choose,  
you will quickly feel right at home.  
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Maximum Compatibility  
Leica engineers were careful to ensure that the  
new Leica M series—like its predecessors—  
remains compatible with existing series. This  
means that objectives, bases, tubes and so on  
can be reused.  
Tubes  
The interface between the optics carrier and the  
tube has remained the same, so existing tubes  
fit the new M series. The new tubes are designed  
for eyepieces with field number 23, while the  
predecessor models were only designed for field  
number 21, resulting in a smaller object field.  
Objectives  
All new objectives of the Leica M series are  
parfocal, meaning that when used with the  
objective nosepiece, they can be replaced while  
keeping the specimen in perfect focus.  
Eyepieces  
However, the new M-series eyepieces have an  
audible and tangible click to provide immedi-  
ate feedback in case of accidental adjustment.  
If you prefer, you can continue to use the previ-  
ous Leica objective series. In this case, parfocal-  
ity is no longer guaranteed.  
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17  
 
On We Go  
If your new Leica microscope has already been  
assembled and commissioned by your Leica  
consultant, click here to skip through the instal-  
lation instructions and go directly to the Quick  
Start Guide on Page 63.  
If, on the other hand, you are assembling  
the microscope yourself, continue with the  
"Assembly" chapter, which begins on Page 19.  
For everything you need to know about the  
correct use of fluorescence-related parts, refer to  
Page 114.  
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Assembly  
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19  
 
Assembling the Focusing Column for MDG Bases  
The first step is to connect the focusing column  
of the M series to the corresponding base.  
Assembling the column adapter  
1. Securely install the column adapter on the  
column using the four included screws.  
Assembling the focusing column  
2. Securely screw the focusing column to the  
base using the six included screws.  
Tools used  
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Hex socket screwdriver, 3 mm  
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20  
 
Assembling the Focusing Column with an Incident-light Base  
When using an incident-light base, the focus-  
ing column and motorized focus are installed  
directly on the base; no extension plate is  
required.  
Assembly  
3. Screw the base securely onto the focusing  
drive.  
1. Place the focusing column on the side.  
Tools used  
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Hex socket screwdriver, 3 mm  
2. Insert the four screws provided into the  
outer holes of the base.  
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21  
 
Motorized Focus: Restricting the Travel Path  
Depending on the work situation, it is  
useful to restrict the maximum travel  
path of the stereomicroscope. This prevents  
injury during handling of the sample caused  
by fingers or hands becoming trapped or the  
specimen touching the objective or even being  
damaged by it.  
Restricting the bottom travel range  
1. Move the motorized focus into the lowest  
position you want to reach.  
3. Push the limit stop to the height of the  
motorized focus.  
It is easiest to move the limit stop by keeping the  
screwdriver inserted and moving it upwards.  
2. Unscrew the screw of the limit stop on the  
side of the focusing column.  
4. Tighten the screw of the limit stop.  
Readjusting the motorized focus  
The motorized focus is factory-adjusted and  
normally does not need to be readjusted—  
even if the maximum travel path is changed.  
Exception: If the power fails while the  
motorized focus is moving, the position  
data are lost. In this case, the calibration must  
be repeated using the Leica LAS software or the  
Leica SmartTouch™. To do so, please consult the  
respective manual.  
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Optics Carrier  
Tools used  
Assembling the optics carrier  
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Hex socket screwdriver, 4 mm  
1. Place the optics carrier on the focusing  
column so that the screw fits into the thread  
provided and the lug fits into the groove.  
2. Press the optics carrier backwards to the  
focusing column and screw it in place using  
your other hand.  
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Tube  
All intermediate tubes that fit between the  
optics carrier and the binocular tube are fitted  
in the same manner.  
Assembling the tube  
2. Push the tube (for example, the inclined  
binocular tube) into the dovetail ring and  
rotate it slightly in both directions until the  
positioning screw meshes with the guide  
groove.  
3. While holding the tube only slightly, care-  
fully tighten the positioning screw. It is  
automatically brought to the correct posi-  
tion.  
Tools used  
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No tools required.  
Preparations  
1. Unscrew the positioning screw and remove  
the protective cover.  
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Eyepieces  
Tools used  
Preparation  
Inserting the eyepieces  
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No tools required.  
1. If you want to use an optional graticule,  
insert it now (Page 79).  
3. Push the eyepieces into the tubes as far as  
they will go and check to ensure that they  
fit tightly and accurately.  
Magnification range  
You can extend the overall magnification range  
using available 10×, 16×, 25× and 40× wide-  
field eyepieces for persons wearing glasses.  
2. Remove the plastic tube guard.  
4. Securely tighten the clamping screws.  
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Objective  
Tools used  
Attaching the objective  
Hold the objective firmly during assem-  
bly and disassembly so that it does not  
fall onto the stage plate. This applies particu-  
larly to the 2x planapochromatic objective,  
which is very heavy. Remove all specimens from  
the stage plate first.  
Alternative fastening options  
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No tools required.  
If using the objective nosepiece, read the  
instructions on Page 28.  
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Preparation  
1. Remove the protective cap on the optics  
carrier by turning it.  
If using the Leica FluoCombi III™, read the  
instructions on Page 31.  
2. Screw the objective clockwise into the  
optics carrier.  
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UV Protection Screen: Assembly  
Tools used  
Use with one objective  
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Allen key  
1. Adjust the UV protection screen laterally  
using the arm.  
Intended use  
2. Unscrew the hexagon-head screw.  
The UV protection screen in front of the speci-  
men plane prevents the user from looking  
directly into the UV rays.  
3. Adjust the UV protection screen using the  
arm.  
Safety Notes  
4. Tighten the hexagon-head screw.  
UV radiation can damage the eyes.  
Therefore, it is mandatory to install the  
UV filter and adjust it correctly.  
5. Fasten the UV protection screen using a  
hexagon-head screw to the left or right side  
of the microscope carrier.  
Always position the UV protection  
screen so that the operator can never  
look directly at the light spot.  
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27  
 
Objective Nosepiece – Assembly  
Preparations  
2. Rotate the moving part by 90° and attach  
the objective nosepiece to the drive hous-  
ing from the front (!). Screw the objective  
nosepiece firmly into place.  
4. Screw the optics carrier onto the objective  
nosepiece.  
Hold the objectives firmly during  
assembly and disassembly so that they  
do not fall onto the stage plate.  
5. Screw both objectives onto the objective  
nosepiece. It makes no difference which  
position an objective occupies.  
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Move the drive housing all the way upwards  
and remove the optics carrier, if the carrier  
has already been installed.  
6. Unscrew the locking screws on both sides  
of the objective nosepiece.  
Assembly  
1. Remove the transport anchor from the  
objective nosepiece.  
3. Unscrew the three Phillips screws on the  
objective mount of the optics carrier and  
remove the intermediate ring.  
You can now adjust the parfocality (see instruc-  
tions on the next page).  
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28  
 
Objective Nosepiece – Adjusting Parfocality  
The following procedure only has to be carried  
out once. Afterwards, both objectives are parfo-  
cal, meaning that the specimen remains in focus  
when the objective nosepiece is rotated.  
Adjustment  
1. Rotate the 2× objective into the beam path  
and set it to the lowest magnification.  
7. Toggle to the 1× objective.  
8. Turn the objective on the thread in both  
directions until the specimen appears  
absolutely sharp.  
2. Focus on the specimen.  
This procedure must be repeated if you replace  
either of the two objectives with another.  
3. Rotate the 1× objective into the beam  
path.  
By means of zooming, check that the behavior  
of the objective is parfocal. Repeat the check  
with the other objective. If it is not parfocal,  
repeat the procedure.  
The following example assumes the combi-  
nation of the 1× and 2× planapochromats. If  
you are using another objective combination,  
replace the 2× objective in the description with  
the objective with the stronger magnification.  
4. Turn the objective on the thread in both  
directions until the specimen appears  
sharp.  
9. Tighten the locking screws.  
5. Toggle to the 2× objective.  
Preparation  
6. Select the strongest magnification and  
refocus until the specimen appears abso-  
lutely sharp.  
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Open the iris diaphragm.  
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Set the dioptric correction of the eyepieces  
to "0".  
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29  
 
Transmitted-light Base TL ST  
Unpacking the base  
Focusing drive and column  
1. Unscrew the extension plate from the base  
using the Allen key provided.  
2. Attach your focusing drive column from  
below using the four hexagon-head  
screws.  
The base is delivered with the adapter plate  
installed. Make sure the instruments are  
unpacked on a flat, sufficiently dimensioned,  
and non-slip surface.  
3. Re-attach the adapter plate to its origi-  
nal position using the six hexagon-head  
screws.  
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30  
 
FluoCombi III™ – Preparations  
Before assembling the FluoCombi™,  
you have to disconnect all instruments  
2. Screw the two screws into the holes  
provided for storage.  
4. Screw the other planapochromatic stereo  
objective into the FluoCombi III™.  
from the power supply. Failure to observe these  
instructions can result in damage to the micro-  
scope and the connected instruments.  
Preparations  
1. Remove the two screws used as transport  
anchors.  
In this way, you can secure the FluoCombi III™  
for transport whenever necessary.  
3. Screw the 5× planapochromat into the  
FluoCombi III™.  
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FluoCombi III™ – Assembly  
1. Guide the FluoCombi III™ in from below,  
while holding it flat. Ensure that it is aligned  
with the holder on the focusing column at  
the left and right.  
2. Hold the FluoCombi III™ securely and  
screw it to the focusing column using the  
provided screw.  
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FluoCombi III™ – Assembly (cont'd.)  
Assembling the optics carrier  
1. Unscrew the three screws and the adapter  
ring on the optics carrier.  
2. Attach the optics carrier to the FluoCombi  
4. Assemble the tube (see Page 24).  
III and screw it into place.  
5. Assemble the illuminator (see Page 51 ff.)  
3. Open the iris diaphragm completely.  
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FluoCombi III™ – Adjusting the Parfocality  
Setting up the objective nosepiece  
The following configuration only has to  
be carried out once. It ensures that the  
parfocality remains intact, and thus the speci-  
men does not need to be brought into focus  
again.  
1. Place a specimen under the microscope.  
7. Unscrew the clamping screw on the  
objective.  
2. Rotate the stereo planachromatic objective  
under the beam path.  
3. Reduce the view so that you can see the  
specimen in the overview.  
4. Center the specimen under the beam path.  
5. Adjust the magnification to the highest  
level and focus on a flat specimen.  
6. Rotate the 5× planachromat under the  
beam path.  
8. Reduce the view so that you can see the  
specimen in the overview.  
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FluoCombi III™ – Adjusting the Parfocality (cont'd.)  
9. By turning the objective ring, focus on the  
specimen until the specimen appears abso-  
lutely sharp.  
11. Refocus.  
12. Tighten the clamping screw (see Step 7).  
13. Rotate the stereo planachromatic objective  
under the beam path.  
This causes the two objectives to be parfo-  
cal. This means that from then on, you can  
toggle between the two objectives without  
refocusing.  
10. Enlarge the view just enough for the center  
of the specimen to be visible in the field of  
view.  
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FluoCombi III™ – Centering the Objectives  
The following configuration only has to  
be carried out once. It ensures that the  
specimen remains in the optical center when  
the objective is changed.  
Centering the objective  
1. Rotate the 5× planachromat under the  
beam path.  
4. Center the objective over the specimen by  
loosening or tightening the screw on one  
side of the objective holder while turning  
the screw on the other side in the opposite  
direction.  
2. Focus on the midpoint of the specimen.  
To attain optimum results for the follow-  
ing settings, insert a graticule into the  
eyepiece. This makes locating the center vastly  
easier.  
3. Rotate the stereo planachromatic objective  
under the beam path.  
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FluoCombi III™ – Filter and UV Protection Screen  
Inserting the dichroic mirror  
1. Pull the dummy filter carrier out of the  
holder.  
Assembling the UV protection screen  
1. Screw the UV protection screen to the  
holder provided on the optics carrier.  
2. Insert the corresponding dichroic mirror.  
2. Orient the UV protection screen so that you  
cannot look directly into the UV light.  
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Transmitted-light Base TL BFDF: Before First Use  
Removing the transport anchors  
Before you can use the transmitted-  
light base for the first time, it is abso-  
lutely necessary to remove the two transport  
anchors.  
Anchor of mirror  
Anchor of switching slide  
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Transmitted-light Base TL BFDF  
Standard delivery  
The selected stage is mounted on the base  
before commissioning. You can switch between  
the stages at any time with just a few hand  
movements.  
Standard stage  
1. Take the glass plate from the rectangular  
gap in the standard stage.  
The base is delivered with the adapter plate  
installed. The selected stage (Leica IsoPro™  
mechanical stage or Leica standard stage  
10 447 269), and the focusing drive will have to  
be mounted later.  
2. Position the stage on the transmitted-light  
base in such way that the four holes align  
over those in the base.  
The following paragraph assumes use of the  
base without the stage mounted. Disassembly  
is performed in reverse order of the following  
steps.  
Stage assembly  
The Leica TL BFDF transmitted-light base can be  
equipped with three different stages.  
3. Attach the stage to the base with the four  
supplied hexagon-head screws.  
ρ
Leica IsoPro™ manual mechanical stage  
Leica IsoPro™ automatic mechanical stage  
4. Insert the glass plate back into the standard  
stage.  
ρ
ρ
Leica standard stage 10 447 269  
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TL RC™ / TL RCI™  
The base is delivered with the adapter plate  
installed. The selected stage (Leica IsoPro™  
mechanical stage or Leica standard stage  
10 447 269), and the focusing drive will have to  
be mounted later.  
Standard stage  
1. Take the glass plate from the rectangular  
gap in the standard stage.  
2. Position the stage on the transmitted-light  
base in such way that the four holes align  
over those in the base.  
Ensure that the instruments are unpacked on a  
level, adequately sized, and nonskid underlay.  
3. Attach the stage to the base with the four  
supplied hexagon-head screws.  
Stage assembly  
The Leica TL RC™/ RCI™ transmitted-light base  
can be equipped with three different Leica  
stages. The selected stage is mounted on the  
base before commissioning. You can switch  
between the stages at any time with just a few  
hand movements.  
4. Insert the glass plate back into the standard  
stage.  
The following paragraph assumes use of the  
base without the stage mounted. Disassembly  
is performed in reverse order of the following  
steps.  
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IsoPro™ Manual Mechanical Stage: Assembly  
Leica IsoPro™ Mechanical Stage  
Before the Leica IsoPro™ mechanical stage is  
Left or right operation  
Before the Leica IsoPro™ mechanical stage is  
mounted to the base, the axis containing the  
control buttons is attached either on the left or  
the right side of the mechanical stage.  
mounted to the base, the axis containing the  
control buttons is attached either on the left or  
the right side of the mechanical stage.  
If the controls are to be mounted on the left-  
hand side, the gear rod on the bottom side of  
the mechanical stage must be unscrewed and  
reattached in reverse.  
If the controls are to be mounted on the left-  
hand side, the gear rod on the bottom side of  
the mechanical stage must be unscrewed and  
reattached in reverse.  
1. Take the glass plate from the mechanical  
stage.  
2. Turn the mechanical stage around and  
place it onto a non-slip surface.  
3. Change the gear rod from the left to the  
right-hand side.  
4. Skip the next two steps to install the  
controls.  
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Leica IsoPro™ Manual Mechanical Stage: Assembly (cont'd.)  
1. Take the glass plate from the mechanical  
stage and turn it around.  
Control assembly  
1. Take the glass plate from the mechanical  
stage and turn it around.  
Mechanical stage assembly  
1. Place the mechanical stage onto the base.  
2. Change the gear rod from the left to the  
right-hand side.  
2. Pull the upper part of the mechanical stage  
carefully towards the user, fixing the lower  
part onto the transmitted-light base.  
2. Attach the axis with the control buttons to  
the desired side. The fastener snaps into the  
mechanical stage magnetically.  
4. Attach the axis with the two supplied hexa-  
gon-head screws.  
5. Attach the cover rail to the mechanical  
stage.  
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Leica IsoPro™ Manual Mechanical Stage: Assembly (cont'd.)  
3. Attach the mechanical stage evenly to the  
three threaded holes.  
Focusing drive and column  
1. Unscrew the extension plate from the base  
using the Allen key provided.  
4. Now move the mechanical stage as far as it  
will go in the direction of the column.  
2. Attach your focusing drive column from  
below using the three hexagon-head  
screws.  
5. Insert the glass plate into the mechanical  
stage.  
3. Re-attach the adapter plate to its original  
position using the three hexagon-head  
screws.  
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Leica IsoPro™ Motorized Mechanical Stage: Assembly  
Basics  
1. Unpack the mechanical stage from the  
transport packaging and position it on the  
transmitted-light base.  
2. Secure the motorized mechanical stage to  
the base using three M4 screws.  
The transmitted light bases of the LeicaTL series  
(TL BFDF, TL RC™, TL RCI™) are supplied with an  
installed extension plate. The selected stage  
(Leica IsoPro™ mechanical stage or standard  
stage 10 447 269) and the focusing drive will  
have to be mounted later.  
1
The motorized mechanical stage is a sensi-  
tive precision instrument. During installation,  
avoid subjecting the stage to impact or severe  
vibrations.  
2
1
2
Microscope base  
Motorized mechanical stage  
3× M4 screws  
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Leica IsoPro™ Motorized Mechanical Stage: Assembly (cont'd.)  
3. Remove the two M3 screws and the holder  
from the mechanical stage.  
4. Remove the two M4 screws and the sleeve  
from the mechanical stage.  
5. Remove the four shock-absorbing cartons  
from the mechanical stage.  
After removal, keep all the transport  
anchors in the plastic bag provided for  
future transport.  
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Leica IsoPro™ Motorized Mechanical Stage: Assembly (cont'd.)  
The bases  
Mechanical stage and base  
Never move the sledge of the motor-  
ized mechanical stage manually in the  
X direction, as otherwise the mechanical system  
will be damaged!  
The TL BFDF, TL RC™ and RCI™ transmitted-light  
bases can be equipped with three different  
stages: Standard stage, manual and automated  
IsoPro™ mechanical stage. The selected stage is  
mounted on the base before commissioning.  
You can switch between the stages at any time  
with just a few hand movements.  
1. Place the mechanical stage onto the base.  
2. Pull the upper part of the mechanical stage  
carefully towards the user and fasten the  
lower part onto the transmitted-light base.  
The following paragraph assumes use of the  
base without the stage mounted. Disassembly  
is performed in reverse order of the following  
steps.  
3. Attach the mechanical stage evenly to the  
three threaded holes.  
4. Now move the mechanical stage as far as it  
will go in the direction of the column.  
5. Insert the glass plate into the mechanical  
stage.  
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Leica IsoPro™ Motorized Mechanical Stage: Assembly (cont'd.)  
Mechanical stage for X-Y stage control  
module  
1. Plug the CTL2 plug of the mechanical stage  
motor into one of the three available CTL2  
interfaces.  
As soon as all instruments have been plugged  
into the control box and it has been plugged  
into the power supply, the mechanical stage  
initializes and automatically drives to the mid  
position.  
2. Plug the CTL2 plug of the Leica PSC control-  
ler into another CTL2 interface.  
4. Connect the PC (where applicable) and  
X/Y Stage DCI Module (using a suitable  
USB cable).  
ρ
The third CTL2 interface is available for  
connecting other instruments, such as the  
Leica foot switch (10 447 398) or TL RCI™  
transmitted light base (10 446 352).  
ρ
The 15-pin Sub-D interface is intended for  
use with the Leica SmartMove™ controller  
(11 501 197).  
3. Plug a power cable into the socket provided  
and into a grounded power socket.  
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Cables: Connections  
The new Leica M-series features extensive  
encoding with which various microscope data  
and settings can be read out, transferred to the  
PC and reproduced later.  
The terminals  
The connection to the PC and to other instru-  
ments is made using the terminals on the rear  
side of the column:  
1. 2 CTL2 terminals for auxiliary equipment  
such as the ring illuminator, the base and  
other accessories from the Leica product  
range.  
1
ρ
The interface to the optics carrier is on the  
column.  
3
2
2. Terminal for the 50-watt power supply  
provided.  
3. USB terminal for the connection to the PC.  
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Cables: Cable Duct  
The integrated cable duct in the column enables  
a neat cable layout around the microscope.  
For example, the USB or FireWire cables of the  
camera can be stowed in the cable duct.  
Feeding the cables  
1. Unscrew the three screws on the cable  
duct.  
3. Place the cables in the cable duct and screw  
the cover on tightly.  
2. Remove the cover of the cable duct.  
Tip: Estimate the length of the cable ends you  
will need before screwing on the cover. For  
thick cables, it is difficult to change the length  
retroactively.  
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Cables: Diagram  
Alternative installation  
Please use the Leica Application  
Suite to configure the functions  
of the system.  
LED5000 RL  
LED5000 MCI™  
DCI Controlbox  
TL RCI™  
PC USB  
Power/USB  
115/230 V  
Footswitch(es)  
Smart Move  
PSC  
SmartTouch  
Cross Stage  
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Leica LED5000 MCI™  
The Leica LED5000 MCI™ (for "Multi Contrast  
Illumination") is installed using two screws. For  
optimum accessibility, the optics carrier should  
be removed during assembly (see Page 23.)  
Assembly  
1. Hold the LED5000 MCI™ with one  
hand and tightly screw the retain-  
ing stirrups on both top holes on the drive  
housing.  
2. Connect the CAN-bus cable provided to  
either of the two sockets. (The flat part of  
the plug must be facing downwards.)  
3. Plug the other end of the cable into one of  
the two "CTL2" sockets on the column.  
Constraints  
The Leica LED5000 MCI™ cannot be used  
together with the objective nosepiece.  
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Leica LED5000 MCI™: Alternative Assembly  
Under certain circumstances, the light source  
must not be moved along with the optics  
carrier. A typical example is multifocus images  
in which the Z-stack changes while the angle  
of incidence of the light must remain the same.  
For such purposes, the Leica LED5000 MCI™ is  
directly fastened to the column.  
2. Screw the retaining stirrup into the column  
3. Push the Leica LED5000 MCI™ onto the  
retaining stirrup.  
at the notch using the single screw. If you  
tighten the screw, the retaining stirrup  
is automatically moved into the correct  
position.  
Installation on the column  
1. Pull the retaining stirrup out of the Leica  
LED5000 MCI™.  
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Leica LED5000 RL  
The ring illuminator, the Leica LED5000 RL  
("Ring Light"), is installed on the objective using  
a single screw. It has been optimized for a work-  
ing distance between 60 and 70 mm.  
Assembly  
3. Plug the other end of the cable into one of  
the two "CTL2" sockets on the column.  
1. Connect the CAN-bus cable to the ring illu-  
minator. The flat part of the plug must be  
facing upwards.  
For optimum accessibility of the specimen,  
the ring illuminator should be installed with  
the cable facing backwards. However, it is  
also possible to turn the ring illuminator side-  
ways, for example if simultaneously using the  
Leica LED5000 MCI™ system illumination. In this  
case, the ring illuminator cannot be connected  
directly to the Leica LED5000 MCI™.  
2. Push the ring illuminator over the objective  
as far as it will go and screw it into place.  
Constraints  
The Leica LED5000 RL can be used in conjunc-  
tion with the planapochromat 1× and planapo-  
chromat 0.63× objectives. With all other  
objectives, the working distance is too low for  
adequate illumination.  
The ring illuminator cannot be used together  
with the objective nosepiece.  
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Leica EL6000 – Safety Notes  
The manufacturer assumes no respon-  
sibility or liability for any use outside of  
the intended use or use outside of the specifica-  
tions from Leica Microsystems Wetzlar GmbH or  
any risks resulting from such use.  
General safety notes  
This safety class 1 device was built and tested  
in accordance with  
EN 61010-2-101:2002  
EN 61010-1:2001,  
IEC 1010-1:2001,  
Safety requirements for electrical equipment  
for measurement, control and laboratory use.  
Unauthorized alterations to the instru-  
ment or noncompliant use shall void all  
rights to any warranty claims.  
If any safety defects or malfunctions  
of the Leica EL6000 are identified, the  
In such cases, the Declaration of Conformity  
shall be invalid.  
instrument must be immediately disconnected  
from the power system and secured against  
additional use. For repair, the Leica EL6000  
must be sent to the supplier or an authorized  
representative of the supplier.  
The devices and accessories described in this  
operating manual have been tested for safety  
and potential hazards.  
This (IVD) device is not intended for use  
in the patient environment defined by  
DIN VDE 0100-710. It is also not intended to  
be combined with medical devices as defined  
by EN 60601-1. If a microscope is electrically  
connected to a medical instrument in accor-  
dance with EN 60601-1, the requirements  
defined in EN 60601-1-1 shall apply.  
The responsible Leica affiliate or the main plant  
in Wetzlar must be consulted whenever the  
device is altered, modified or used in conjunc-  
tion with non-Leica components that are  
outside of the scope of this manual.  
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Leica EL6000 – Safety Notes (cont'd.)  
The Leica EL6000 compact light source  
generates high-energy light with invisi-  
The interior of the lamp inserted into the  
unit contains highly toxic substances.  
Only fuses of the specified type and  
the listed rated current may be used as  
replacements. The use of incorrect fuses may  
result in a fire hazard.  
ble components. There is a risk of being dazzled  
or blinded by light! Never look directly into the  
light guide output of the instrument or into  
the output of the light guide connected to the  
instrument. Always ensure that the output of  
the connected light guide is securely connected  
to the system to be illuminated before switch-  
ing on the compact light source. Furthermore,  
before switching on the compact light source,  
dim the light output all the way using the  
intensity switch (left limit stop of the switch) to  
prevent damage to the connected system.  
At the end of its service life, dispose of the lamp  
according to applicable regulations. The manu-  
facturer of the lamp provides corresponding  
information, for example in the lamp's shipping  
documents. Follow the manufacturer's instruc-  
tions in case the lamp bursts.  
The instrument is intended exclusively  
for operation in dry rooms. Do not  
use the instrument in rooms with explosion  
hazard.  
The Leica EL6000 compact light source  
is designed for a voltage range of  
100 – 240 VAC, 50 – 60 Hz. Within this voltage  
and frequency range, the instrument always  
adapts to the connected power supply. Operat-  
ing the instrument with a power supply voltage  
outside this range can destroy the instrument  
and the connected components!  
To prevent damage to the light guide  
connected to the device, the heat-  
absorbing filter inserted into the device must  
be free of damage (gaps, cracks etc.). If the  
heat-absorbing filter is not inserted or is defec-  
tive, the service life of the light guide will be  
decreased.  
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Leica EL6000 – Safety Notes (cont'd.)  
Electrical safety  
For indoor use only.  
Supply voltage  
Frequency  
100–240 V~ ( 10%)  
50–60 Hz  
Power consumption  
Fuses  
Max. 210 VA  
5×20, 2.5 A, slow-blowing, breaking capacity H, see Page 113  
Ambient temperature  
Relative humidity  
Overvoltage category  
Pollution degree  
0 – 40 °C  
10%–90%  
II  
2
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56  
Leica EL6000 – Preparations  
Setting up the instrument  
The lamp used in the instrument  
becomes very hot during operation and  
has high internal pressure when hot. Before  
changing the lamp, it is mandatory to allow the  
instrument to cool off for at least 20 minutes.  
Inserting the lamp  
Set up the Leica EL6000 so that the front  
1. Pull the power plug out of the socket, so  
that the EL6000 is disconnected from the  
power system.  
is readily accessible and visible.  
ρ
The ventilation slots on the sides and back  
2. Unscrew both screws of the cover using a  
3 mm Allen key.  
panel of the device must not be covered.  
The Leica EL6000 compact light source  
ρ
Maintain a free room of at least 150 mm on  
the rear panel of the instrument.  
comes with a factory-supplied lamp,  
but the lamp is not installed when shipped. This  
minimizes the danger of damage to the lamp  
during transport.  
Instructions for lamp replacement  
The lamp contains mercury! Be abso-  
Before transporting the Leica EL6000  
lutely certain to follow the handling  
instructions and safety notes provided with the  
lamp.  
compact light source, you first have to  
remove the lamp.  
3. Remove the housing cover.  
Maintain cleanliness when inserting the  
lamp. Remove any clinging packaging  
materials.  
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Leica EL6000 – Preparation (cont'd.)  
4. Carefully lay the Leica EL6000 on its side so  
that the opening faces you.  
5. Pull the pressure bolt back towards the  
front plate using the lever.  
Ensure that the groove in the contact surface of  
the lamp matches up with the corresponding  
plug in the lamp mount.  
This makes it easier to insert the lamp.  
6. Insert the lamp.  
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Leica EL6000 – Connection to the Fluorescence Lamp Housing  
Always connect the light guide to the  
lamp housing of the stereomicroscope  
in order to prevent danger to the user from the  
high-energy light.  
2. Insert the adapter into the fluorescence  
lamp housing and retighten the locking  
screw.  
4. Insert the short end of the light guide into  
the lamp housing of the stereomicroscope  
as far as it will go.  
5. Securely tighten the clamping screw.  
1. Unscrew the positioning screw and remove  
the protective cover of the fluorescence  
lamp housing.  
3. Unscrew the three red protective caps on  
the light guide.  
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Leica EL6000 – Preparation (cont'd.)  
7. When the lamp makes full contact with the  
lamp mount, release the lever.  
9. Check to make certain that a heat-absorb-  
ing filter has been inserted into the shaft in  
order to protect the connected light guide.  
8. Connect the plug of the lamp with the  
coupling in the instrument.  
Ensure that no wires are touching the reflector  
of the lamp.  
10. Close the housing cover and insert the  
screws.  
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Leica EL6000 – Replacing the Lamp  
The procedure for replacing the lamp does not  
differ from the installation procedure outlined  
on Page 57, except for the fact that the existing  
lamp has to be removed first.  
3. Remove the housing cover.  
4. Carefully lay the Leica EL6000 on its side so  
that the opening faces you.  
Replacing the lamp  
This makes it easier to insert the lamp.  
The lamp used in the instrument  
becomes very hot during operation and  
has high internal pressure when hot. Before  
changing the lamp, it is mandatory to allow the  
instrument to cool off for at least 20 minutes.  
5. Pull the pressure bolt back towards the  
front plate using the lever.  
6. Pull out the lamp and disconnect the plug  
from the coupling in the instrument.  
1. Pull the power plug out of the socket, so  
that the EL6000 is disconnected from the  
power system.  
7. Install the new lamp as outlined on Page 58,  
beginning with item 6.  
2. Unscrew both screws of the cover using a  
3 mm Allen key.  
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Leica EL6000 – Connection to the Fluorescence Lamp Housing (cont'd.)  
6. Insert the long end of the light guide into  
the light output of the Leica EL6000. There  
must be a noticeable click.  
Only use a light guide with a light input  
of the type "Storz long", as otherwise  
damage to the instrument and danger to the  
user can result (risk of being dazzled).  
Before you open the shutter, the light  
guide must be connected on both  
sides. Otherwise, the escaping light can cause  
injury to eyes and skin and damage to furni-  
ture. Never look into the light escaping from  
the light guide!  
5. Connect the Leica LA6000 to the power  
system using the power cable.  
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Quick Start Guide  
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The Fastest Route to Success  
Your Leica stereomicroscope has been delivered in completely assembled  
condition by your Leica partner, and naturally you want to get right to  
work. Therefore, your next step should be to study the Quick Start Guide,  
which outlines the most important steps at a glance.  
This manual will then familiarize you with the finer details of your micro-  
scope. The following pages contain important, practical information that  
makes using it every day easier.  
Take time to read it – it's worth it!  
The M series Quick Start Guide (included with instrument).  
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64  
 
Overview of an M Series Microscope  
1
Eyepieces for spectacle wearers with dioptric correction  
and eyecups  
2
3
4
5
6
7
8
9
Trinocular tube  
Fluorescence housing  
Filter Changer  
Display  
Motorized Focus  
Objective Nosepiece  
Leica SmartTouch  
UV protection screen  
1
2
3
4
5
6
7
9
8
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65  
 
The Correct Interpupillary Distance  
The interpupillary distance is correctly set if you  
see a single circular image field when looking  
at a specimen.  
Adjusting the interpupillary distance  
1. Look into the eyepieces.  
3. Slowly approach the eyepieces with your  
eyes until you can see the complete image  
field without corner cutting.  
2. Hold the eyepieces with both hands. Push  
the eyepieces together or separate them  
until you see a circular image.  
If you are still a novice microscope user, you  
may need a short time to become accustomed  
to this. Not to worry—after a little while, it will  
become automatic.  
Reference value  
The distance between eye and eyepiece  
measures approx. 22 mm for 10/23B wide-field  
eyepieces for persons wearing glasses.  
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Using the Eyepieces  
The eyepieces form the connection between  
the tube and the eye of the observer. Simply  
push them into the tube and they are ready to  
use.  
If you do not wear glasses:  
1. Hold the eyepiece firmly and rotate the  
eyecups forwards counterclockwise.  
If you wear glasses:  
1. Hold the eyepiece firmly and rotate the  
eyecups clockwise towards the rear, as  
otherwise the viewing distance is too  
great.  
2. If an eyepiece is equipped with the inte-  
Each eyepiece offers a certain magnification  
factor that has a determinative effect on the  
total magnification. Furthermore, all Leica  
eyepieces can be equipped with practical grati-  
cules that enable measuring and quantifying of  
specimens.  
Dioptric correction  
A built-in dioptric correction is available for  
eyeglass wearers. For more information, refer  
to Page 77.  
grated dioptric correction, turn the value to  
the "0" mark.  
2. If an eyepiece is equipped with the inte-  
grated dioptric correction, turn the value to  
the "0" mark.  
By the way, one benefit of viewing with  
eyeglasses is a drastically lower risk of bacte-  
rial transmission (see Page 76). The soft mate-  
rial of the eyecup also ensures that your glasses  
will not be scratched, even if they contact the  
eyepiece.  
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67  
 
Focusing  
Focusing raises or lowers the stereomicroscope  
using the focusing drive. The specimen detail is  
brought into sharp focus as soon as it is in the  
focal point of the objective.  
Focusing  
Coarse/fine adjustment  
ρ
The inner, coarse adjustment is used for  
The sharpness is adjusted using the coarse/fine  
adjustment. The resolution of the coarse/fine  
adjustment is 1 µm.  
covering great distances.  
ρ
The outer, fine adjustment is used for fine  
focusing.  
ρ
The focusing drive can be operated either  
2. The coarse/fine adjustment carries a  
left- or right-handed.  
load of up to 15 kg.  
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68  
 
Adjusting the Resistance of the Focus Drive  
Adjusting the resistance  
Is the focus movement too loose or too tight?  
Does the outfit tend to slide downwards? The  
resistance can be adjusted individually depend-  
ing on the equipment weight and personal  
preferences as follows:  
1. Grip the outer drive knobs with both hands  
and turn them towards each other until  
the desired resistance is reached during  
focusing.  
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69  
 
Changing Magnification (Zoom)  
All M series microscopes have an integrated  
zoom. The name indicates the zoom range  
covered:  
Zooming  
1. Look into the eyepieces.  
2. Focus on the specimen.  
ρ
Leica M165 C = 16.5:1  
ρ
Leica M205 C = 20.5:1  
3. Rotate the magnification changer until the  
desired magnification is configured.  
The rotary knob for the zoom can be used either  
left or right-handed.  
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70  
 
Ratchet Steps and Magnification Levels  
The zoom button can optionally be operated  
either with or without ratchet steps. Continu-  
ous zoom is possible when the ratchet steps are  
disabled, which many users find convenient.  
On the other hand, when the ratchet steps are  
enabled, photographs, measurement results  
etc. can be reproduced more accurately.  
Enabling and disabling ratchet steps  
1. Push the top button downwards to disable  
the ratchet steps.  
Magnifications and fields of view  
The formula on Page 147 provides additional  
information about the magnifications and field  
of view diameters, with consideration given to  
the position of the magnification changer and  
the eyepiece and objective combination used.  
2. Push the bottom button upwards to enable  
the ratchet steps.  
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71  
 
Parfocality: More Comfort and Convenience for Your Work  
All Leica stereomicroscopes are parfocally  
matched, meaning that you can view a focused  
specimen from the lowest to the highest  
magnification without having to refocus. The  
focus needs only be readjusted if you want to  
see a specimen location that is located higher  
or lower.  
Parfocality  
1. Enlarge the view to the maximum level.  
2. Focus on the specimen.  
You are done! Even if you select a smaller work-  
ing distance, the specimen remains pin-sharp.  
Requirements for parfocal work  
The parfocality is maintained until you focus on  
another level of the specimen.  
ρ
If you are using an eyepiece with dioptric  
correction, the procedure differs from this  
description. For more information, refer to  
Page 78.  
ρ
For the procedure for adjusting the parfo-  
cality for the objective nosepiece, refer to  
Page 29.  
ρ
For the procedure for adjusting the parfo-  
cality for the Leica FluoCombi III™, refer to  
Page 34.  
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72  
 
Iris Diaphragm  
The iris diaphragm in the optics carrier of your  
M series microscope fulfills the same purpose  
as the iris diaphragm in a camera: it regulates  
the available light, which changes the depth  
of field. The "depth of field" (or "focus depth")  
is the area of a specimen that is brought into  
sharp focus.  
Closing the iris diaphragm  
Opening the Iris Diaphragm  
ρ
ρ
Close the iris diaphragm by turning the  
Open the iris diaphragm by turning the  
knob to the left. The subject appears darker  
and the depth of field increases.  
knob to the right. The subject now appears  
brighter, but the depth of field decreases.  
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73  
 
Eyepieces  
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74  
 
Magnification Factors of the Eyepieces  
An eyepiece not only makes it possible to look passively into the micro-  
scope, but also has a critical effect on the maximum magnification. The  
magnification factor is between 10x and 40x.  
The following eyepieces are available for the M series:  
Magnification  
Dioptric correction  
5 diopter settings  
5 diopter settings  
5 diopter settings  
5 diopter settings  
Order number  
10 450 023  
10 450 024  
10 450 025  
10 450 026  
10×  
16×  
25×  
40×  
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75  
 
Health Notes  
Potential sources of infection  
Direct contact with eyepieces is  
a
potential transmission method for  
bacterial and viral infections of the eye. The risk  
can be kept to a minimum by using individual  
eyepieces or detachable eyecups. Eyecups can  
be ordered separately. Please contact your  
Leica partner.  
Separate eyecups are an effective  
way of preventing infections.  
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76  
 
Dioptric Correction  
All Leica eyepieces are also available with built-  
in dioptric correction, allowing the microscope  
to be used without glasses even by those with  
Using the Dioptric Correction  
1. Set the dioptric correction of both eyepieces  
to the mid position ("0" diopter settings).  
Note that when using dioptric correction,  
the advantage of parfocality is lost—thus  
you have to manually refocus each time you  
change the zoom level. To also use parfocality  
with dioptric correction, refer to the instruc-  
tions on Page 78.  
vision problems. The correction comprises  
diopter settings.  
5
2. While wearing your glasses, look through  
the eyepieces and focus on the specimen.  
3. Rotate both eyepieces to the maximum  
value of "+5".  
4. Hold one eye closed and rotate the other  
eyepiece in the "-" direction until the speci-  
men appears sharp.  
5. Then, open the other eye and correct the  
diopter settings until the image is uniformly  
sharp.  
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77  
 
Dioptric Correction and Parfocality  
Leicastereomicroscopesareparfocallymatched.  
The prerequisite for this is the correct setting of  
the diopters and the parfocality. The following  
adjustments only have to be carried out once  
by each user.  
Adjusting  
7. Look into the eyepieces.  
1. Set the dioptric correction for both  
eyepieces to "0".  
8. Slowly rotate each eyepiece individually  
in the "–" direction until each eye sees the  
object sharply imaged.  
2. Select the lowest magnification and focus  
on a flat specimen.  
9. Select the highest magnification and  
refocus if necessary.  
Preparations  
3. Select the highest magnification and read-  
just the sharpness.  
ρ
Move the lever of the video/phototube to  
the "observation" position and open the  
diaphragm.  
Now, if you adjust the magnification from the  
lowest to the highest level, the specimen is  
always brought into sharp focus. If not, repeat  
the process.  
4. Select the lowest magnification again, but  
do not look into the eyepieces.  
ρ
If you are using the microscope carrier AX,  
set it to stereoscopic observation.  
6. Rotate the eyepieces counterclockwise  
in the "+" direction as far as they will go  
(+5 diopter settings).  
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78  
 
Graticules  
Use  
2. Clamp the graticule on the insert, applying  
moderate pressure. Ensure that the grati-  
cule fits tightly.  
4. You can now align the graticule by rotating  
the eyepiece in the tube and then tighten-  
ing it using the clamping screw.  
Leica graticules make length measurements  
and counting easier, particularly for work-  
stations that are not equipped with a digital  
camera and LAS software.  
The Leica graticules for length measurements  
and numbering are fitted in mounts and are  
inserted into the eyepieces.  
1. Screw the insert off of the eyepiece.  
3. Screw the insert and graticule firmly into  
place and replace the eyepiece in the tube.  
Use with the Leica AX carrier  
If possible, measure with the micro-  
scope carrier AX in vertical position. The  
measurements are more accurate without the  
convergence angle in the stereoscopic image.  
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Photography & Video  
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80  
 
Photography & Video  
For most microscope users, digital documen-  
tation has become an invaluable part of their  
work. Research results can be presented in an  
attractive manner; measurements on the digital  
image provide clarity and, in conjunction with  
the motorized IsoPro™ mechanical stage, even  
images of large specimens can be captured  
step by step and automatically joined to create  
a new complete image.  
Leica DFC cameras  
Leica Application Suite  
However, if you require absolute control  
over the camera and need the capability for  
measurement, evaluation and more in addition  
to photography, the digital Leica DFC cameras  
are exactly right for you. Together with the  
Leica Application Suite, they provide virtually  
limitless freedom of use. For additional informa-  
tion about Leica cameras, refer to the camera's  
documentation.  
The "Leica Application Suite", or "LAS" for short,  
is, as it were, the digital extension of the Leica  
M series microscopes. In addition to capturing  
images, it lets you control the microscope, illu-  
minator, stages, cameras and more. For addi-  
tional information, refer to the LAS online help.  
Adapter  
If camera control using the Leica Application  
Suite is not required, conventional mirror reflex  
and rangefinder cameras from third-party  
manufacturers can be used. For this purpose,  
Leica Microsystems offers a variety of adapters  
that can be used together with the 50% and  
100% trinocular tubes.  
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81  
 
Photo Tubes and C-mounts  
Application  
If there is unwanted shading at the corners even  
with a compatible C-mount adapter installed, it  
can be corrected using the "Shading function"  
of the camera software.  
Cameras from third-party suppliers  
All Leica DFC cameras are equipped with a  
standardized C-mount interface. In turn, the  
C-mount adapter for the respective trinocular  
tube is connected to this interface. This adapter  
creates a solid mechanical connection between  
the microscope and camera and ensures opti-  
mum rendering of the microscopic image on  
the image sensor of the camera.  
In addition to Leica DFC cameras with the stan-  
dardized C-mount interfaces, you can connect  
third-party cameras to the microscope using  
a T2 bayonet adapter. To do so, instead of the  
C-mount adapter, simply use the correspond-  
ing SLR adapter with T2 connection. However,  
these third-party cameras are not integrated  
into the Leica Application Suite and have to  
be operated using the corresponding software  
from the camera manufacturer.  
Alternatively, you can also use a C-mount  
adapter with higher magnification. This primar-  
ily avoids the critical border area of the field of  
vision and concentrates on the center of the  
field of vision.  
Usually, the ideal is for the digital camera to  
capture as much of the field of vision as possi-  
ble, while excluding as much of the black edge  
of the field of vision as possible. To do so, the  
magnification factor of the C-mount adapter  
must match the image format of the sensor as  
closely as possible (see table).  
Camera  
optimal  
(large  
suitable  
(smaller  
The Leica digital cameras are detailed in a sepa-  
rate user manual along with instructions for  
their assembly and use.  
image field)  
image field)  
DFC290  
DFC420  
DFC490  
DFC500  
0.5×  
0.5×  
0.63×  
0.63×  
0.8×  
0.63×  
0.63×  
0.8×  
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82  
 
Trinocular Video/Phototube 50%  
Use  
With its third beam path, the trinocular video/  
phototube 50% enables you to simultaneously  
view and photograph a specimen. The available  
light is divided as follows:  
ρ
50% is available for the two eyepieces.  
ρ
50% of the light is diverted to the video/  
photo beam path.  
Assembly  
Fasten the "trinocular tube 50%" to the optics  
carrier instead of the binocular observation  
tube (refer to Page 24).  
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Trinocular Video/Phototube 100%  
Use  
Switchover  
ρ
With its third beam path, the trinocular video/  
phototube 100% enables you to either view or  
photograph a specimen. This means that 100%  
of the light is available to one or the other beam  
path. The other beam path remains opaque or  
black.  
Turn the controller on the right side of the  
tube into the horizontal position in order to  
guide all available light into the eyepieces.  
You can now observe the specimen.  
ρ
Turn the controller on the right side of the  
tube into the vertical position in order to  
guide all available light into the camera.  
You can now photograph the specimen.  
Assembly  
Fasten the "trinocular tube 100%" to the optics  
carrier instead of the binocular observation  
tube (refer to Page 24).  
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84  
 
Microscope Carrier  
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85  
 
The Objective Nosepiece  
Use  
Parfocal work  
Technical constraints  
The objective nosepiece cannot be  
used together with the LED5000 MCI™  
system illumination, as the objective nosepiece  
can no longer be rotated.  
The objective nosepiece enables you to switch  
between two objectives using just one hand  
movement, for example between a 1× and a 2×  
planapochromat.  
With the new M series objectives, the parfo-  
cality is maintained even when objectives are  
changed, meaning that the specimen remains  
in sharp focus during the change.  
Older Leica objectives can continue to be  
used, but without parfocality during the  
objective change.  
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86  
 
Objectives and  
Optical Accessories  
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87  
 
The Different Types of Objectives  
To meet the various requirements regarding  
imaging properties, there is a choice of high-  
quality interchangeable planachromatic and  
planapochromatic objectives and also lower-  
priced interchangeable achromatic objectives.  
Achromatic objectives  
Achromatic objectives with a long focal  
length  
For special applications, achromatic objectives  
with long working distances and focal lengths  
of f=100 mm to 400 mm are available.  
The 0.32×, 0.5×, 0.63×, 0.8×, 1×, 1.5×, 2×  
achromatic objectives offer countless variants  
for selecting the object field diameter, magni-  
fication ranges and working distances (see  
Page 147).  
ρ
Achromatic objectives are particularly  
suited for specimens with high-contrast  
structures.  
Planachromatic objective 1×  
For the highest requirements for overall image  
quality, we recommend equipping the micro-  
scope with the 1× plan (flat-field) objective,  
which returns sharp, contrast-rich object fields.  
ρ
Flat-field (planachromatic) objectives are  
particularly well suited for studying flat  
objects such as wafers and thin sections.  
ρ
With planapochromatic objectives, the  
finest structures are visible with high  
contrast. The sophisticated apochromatic  
correction allows these objectives to attain  
the highest color brilliance and fidelity.  
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88  
 
Bases  
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89  
 
Leica TL ST Transmitted-light Base: Controls  
1
2
1
2
3
3
4
Extension plate of the transmitted-light base TL ST  
Rear side of the transmitted-light base TL ST  
1
2
3
Screws for changing the halogen lamp  
Power connection socket  
Power switch  
1
Adapter plate for easy assembly of focusing  
drives  
2
3
4
Removable glass plate  
Controller for light intensity  
Adjustment for deflection mirror  
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90  
 
Leica TL ST Transmitted-light Base: Operation  
Light intensity control  
Transmitted-light control  
Bright field  
The left control adjusts the intensity of the  
12V/20W halogen illumination.  
The transmitted-light base TL BFDF has a slider  
that automatically moves the deflection mirror  
in the base when moved. The mirror is kept in  
the correct position at all times and permits  
smooth changeover between bright field and  
opaque transmitted light.  
Bright field is suitable for examining translu-  
cent objects featuring contrasting structures.  
The object is directly illuminated from below  
and is seen in its natural colors against a bright  
background.  
1. Switch on the illumination of the base at  
the power switch.  
ρ
2. Focus on the specimen.  
Move the slider backwards until the desired  
effect is achieved.  
3. Set the illumination to the desired intensity  
using the left control.  
Inclined transmitted light  
Transmitted light that traverses the object  
obliquely will provide additional resolution and  
information when observing semitransparent,  
opaque objects.  
ρ
Slowly pull the slider towards yourself until  
the desired effect is achieved.  
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Leica TL ST Transmitted-light Base: Changing Bulbs  
Changing the halogen lamp  
Before you change the lamp, it is abso-  
lutely necessary to unplug the power  
plug from the base to prevent the risk of electric  
shock!  
Changing bulbs  
Precautionary measures  
When inserting the lamp, ensure that  
the cables are inside the two metal  
clamps. This prevents the cables from getting  
caught during insertion.  
1. Unscrew the two screws on the heat sink  
and pull the heat sink out, along with the  
lamp.  
The halogen lamp becomes very hot  
during operation. Therefore, to avoid  
being burned, let the base cool off for approx.  
10 minutes after switching it off!  
Do not touch new halogen lamps with  
your bare fingers—this drastically  
reduces the service life of the lamp!  
2. Carefully pull out the lamp and mount by  
pulling them upwards.  
3. Disconnect the lamp from the mount.  
4. Insert the new lamp into the mount and  
reinsert the lamp holder.  
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Leica TL BFDF Transmitted-light Base: Controls  
1
2
Adapter at the focusing drive  
3
Extension plate of the Transmitted-light base TL BFDF  
1
Adapter plate for easy assembly of focusing  
drives  
2
3
Standard stage 10 447 269  
Button to toggle between bright field and  
dark field  
Connector for cold light sources  
(light conductor active f = 10mm,  
end tube f = 13mm)  
Button to toggle between bright field and dark field  
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Leica TL BFDF Transmitted-light Base: Operation  
Light intensity control  
Observe the user manual—in particu-  
lar, all safety regulations—from the  
manufacturers of the light guide and cold light  
source.  
Bright field  
Dark field  
Bright field is suitable for examining translu-  
cent objects featuring contrasting structures.  
The object is directly illuminated from below  
and is seen in its natural colors against a bright  
background.  
In dark-field illumination, a ring illuminator is  
used in such a way that the direct light does  
not reach the objective without a specimen.  
Only the structure of semitransparent, opaque  
objects disperses the light, making the object  
visible against a dark background.  
ρ
Switch on the cold light source according to  
the manufacturer's user manual and adjust  
the brightness.  
ρ
Turn the control as far as it will go towards  
ρ
"BF" ("bright field").  
Turn the control as far as it will go towards  
"DF" ("dark field").  
Transmitted-light control  
The Leica TL BFDF transmitted-light base has  
a control that switches the light from "bright  
field" to "dark field".  
Fingertip with bright field illumination  
Identical subject with dark field illumination  
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94  
 
Leica TL RC™ / TL RCI™: Controls  
1
2
1
2
3
4
5
6
7
3 4 5  
6
Vertical column - transmitted-light base  
adapter plate  
1
2
3
4
5
6
Power switch  
Power connection socket  
USB socket, type B  
USB socket, type A  
2 CAN bus  
1
Heat sink of the integrated halogen illumina-  
tion (only TL RCI™)  
2
3
4
5
Extension plate for focusing drives  
Standard stage 10 447 269  
Filter holder  
Control of top and bottom flaps of the  
Rottermann Contrast™  
Screws for changing the halogen lamp  
6
7
Button for mirror and horizontal movement  
of the mirror  
Transmitted-light base  
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95  
 
Leica TL RCI™: The Deflection Mirror  
Tilted mirror  
Functions of the rotary knob  
The built-in mirror features one flat and one  
concave side and can be rotated and moved.  
The concave side has been specially designed  
for the optical requirements of objectives with a  
high numerical aperture. The black rotary knob  
on the left side of the transmitted-light base  
can be used to rotate the built-in path-folding  
mirror and move it forwards/back.  
The rotary knob (1) fulfills the following tasks:  
ρ
Turning the deflection mirror from the flat  
to the concave side  
ρ
Slight tilting to guide the light beam  
through the specimen plane at a steeper or  
flatter angle  
1
ρ
The concave cutout on the handle indicates the  
concave side of the mirror, allowing intuitive  
operation at any time without eye contact.  
Moving the deflection mirror (forwards/  
back)  
Inverted world?  
Depending on the properties of the specimen  
(refractive index of the environment) and the  
perception of the viewer, it is possible that  
the switches described below for positive and  
inverted relief contrast are to be operated  
in reverse. This means that the lower switch,  
rather than the upper switch, controls inverted  
the relief contrast and vice-versa.  
The angle of light incidence in the specimen  
plane changes depending on the tilt and posi-  
tion of the mirror. As a result, switching between  
transmitted light bright field, oblique illumina-  
tion and dark field-like illumination is possible.  
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96  
 
Leica TL RCI™: Color Intensity and Temperature  
The transmitted-light base TL RCI™ has two  
electronic potentiometers that control the color  
intensity (1) and color temperature (2).  
Using a USB mouse (only TL RCI™)  
The Leica USB mouse controls the CCIC™ and  
dimming function of the TL RCI™ base. Connect  
the mouse to the corresponding USB port of  
the base.  
The controller for the color temperature simul-  
taneously serves as an electronic shutter:  
ρ
The scroll wheel of the mouse is occupied  
ρ
To interrupt your work, click the potentiom-  
eter (2).  
by default with the CCIC™ control system  
and is used to control the illumination  
intensity.  
1
2
ρ
Click again to switch on the illumination.  
ρ
The electronics returns the color tempera-  
ture to the previously configured settings.  
To switch the illumination on or off, briefly  
click the scroll wheel.  
1
2
Potentiometer for controlling the CCIC™  
(Constant Color Intensity Control) illumina-  
tion intensity  
Potentiometer for controlling the color  
temperature  
ρ
To enter or exit dimming mode, click and  
hold down the scroll wheel for longer than  
2 seconds.  
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97  
 
Leica TL RC™ / TL RCI™: Operation  
Setting the relief contrast  
Depending on the flap position, a part of  
Increased contrast without relief is attained  
if both diaphragms are set to 45°. A gap-like  
illuminated area is created. By tilting the deflec-  
tion mirror slightly, you can move the gap over  
the entire field of view and quickly toggle  
between positive and negative relief images.  
The dynamic effect makes it easy to distinguish  
phase structures from amplitude structures.  
The two switches on the left side of the trans-  
mitted-light base TL RC™/TL RCI™ activate two  
built-in flaps. The outer switch (1) controls the  
inverted relief contrast, and the inner switch (2)  
adjusts the positive relief contrast.  
the opening of the built-in Fresnel lenses are  
covered, which results in the different contrast  
effects. Phase structures typically act as spatial,  
relief-type images—in the positive relief  
contrast like hills, in the inverted relief contrast  
like valleys.  
1
2
3
1
2
3
Switch for adjusting the inverted relief  
contrast  
Switch for adjusting the positive relief  
contrast  
Deflection mirror  
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98  
 
Leica TL RCI™: Methods in Transmitted Light  
Vertical bright-field illumination  
Suitable for stained amplitude specimens with  
sufficient contrast.  
Inclined transmitted light  
Single-sided dark field  
Suitable for fixed specimens and fine struc-  
tures.  
Suitable for semitransparent, opaque speci-  
mens such as foraminifera and fish eggs. Move  
the deflection mirror until the desired data are  
visible.  
The light beams are deflected vertically through  
the specimen. This results in an accurate bright  
field with maximum brightness.  
The flatter the angle at which the light beams  
are deflected into the specimen plane, the  
darker the substrate appears. A dark field-like  
transmitted light is created. Outlines, fine edges  
and structures are bright, in contrast with the  
dark background, through diffraction of the  
light beams on the dark background.  
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99  
 
Leica TL RCI™: Relief Images  
Starting position  
Positive relief contrast  
Negative relief contrast  
Suitable for semitransparent and transparent  
specimens. The phase structures look like hills.  
Suitable for semitransparent and transparent  
specimens. These settings result in a nega-  
tive relief contrast. Phase structures look like  
valleys.  
1. Push the deflection mirror all the way back  
towards the column.  
The effect can be strengthened or weakened by  
gently tilting the deflection mirror.  
2. Turn the deflection mirror into the notch  
position at an angle of 45°.  
The effect can be strengthened or weakened by  
gently tilting the deflection mirror.  
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100  
 
Leica TL RCI™: Relief Images (cont'd.)  
Dynamic relief contrast  
Constraints  
Suitable for semitransparent and transparent  
specimens.  
The relief methods provide good results from  
mid-zoom to high magnifications and with 1×,  
1.6× and 2× objectives. In the lower zoom half  
and with weaker specimens, the object field  
may not be uniformly illuminated.  
By tilting the deflection mirror slightly, you can  
move the gaps over the entire field of view and  
quickly toggle between positive and negative  
relief images. The dynamic effect makes it easy  
to distinguish phase structures from amplitude  
structures.  
We recommend using the transmitted-light  
base with 1× or higher objectives, and not  
objectives with a long focal length.  
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101  
Using Filters  
Filters for Leica TL RC™ and TL RCI™  
The transmitted-light bases TL RC™ and TL RCI™  
can be equipped with up to three filters—  
available as accessories—simultaneously. By  
customer request, the filters are also available  
as one-off items.  
2. Take the empty filter from an available filter  
slot in the filter holder.  
Daylight filter for Leica TL ST  
A daylight filter is also available for the LeicaTL ST  
transmitted-light base.  
3. Insert the desired filter.  
1. Switch off the light source or click  
(Leica TL RCI™) the button for the shutter.  
4. Switch the light source back on.  
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102  
 
Leica IsoPro™ (Non-motorized): Controls  
Operating the Leica IsoPro™ mechanical  
stage  
1. To move the stage in the X direction, rotate  
the outer knob.  
2. To move the stage in the Y direction, rotate  
the inner control ring.  
1
2
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103  
 
Leica IsoPro™ (Motorized): Controls  
IsoPro  
X/Y Stage DCI module  
Leica PSC Controller  
1
1
2
2
3
1
2
3
4
1
2
3
4
Sub-D interface for Leica SmartMove™  
3 CTL2 interfaces  
USB interface (type B)  
1
2
3
Quick control/memory function  
Fine control in X direction  
Fine control in Y direction  
1
2
Leica IsoPromotorized mechanical stage  
Housing with motorization  
Socket for grounded power cable  
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104  
 
System Illumination  
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105  
 
Leica LED5000 MCI™  
Use  
Contact with the base  
If the optics carriers are accidentally  
lowered too far, contact between the  
base and MCI may result. A safety mechanism  
in the linkage ensures that, in this case, the MCI  
is automatically pushed upwards to prevent the  
possibility of damage.  
The Leica LED5000 MCI™ (for "Multi Contrast  
Illumination") is a universal high-output illu-  
minator. Three groups of 3 LEDs each can be  
arranged as desired around the specimen. The  
targeted control of the LEDs enables various  
illumination scenarios to be implemented.  
Preparation  
Installed too high  
ρ
ρ
Be sure not to place any specimens directly  
beneath the MCI.  
Hold the MCI with both hands and pull it down-  
wards until the illuminator clicks into place on  
the bottom end of the guide rods.  
After the optics carrier is lifted, put the MCI  
back into the original position.  
In this position, you always have the same  
contrast with identical illumination. This guar-  
antees the reproducibility of an experiment.  
Optimum height  
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106  
 
Leica LED5000 MCI™ (cont'd.)  
Using the keyboard  
The illumination scenarios  
ρ
Use the key to switch the illumination on  
or off.  
Use the " " and " " keys to toggle between the  
illumination scenarios shown below.  
ρ
Use the "+" and "–" keys to adjust the  
Maximum brightness  
brightness in 10 increments. Touch either  
of the two buttons to adjust the intensity in  
small increments. Hold a key to change the  
intensity more quickly.  
For temperature reasons it is not possible to  
switch on all nine LEDs simultaneously. There-  
fore, to provide bright overall illumination, the  
top two rows are activated. The bottom row  
primarily provides contrast.  
The Leica LED5000 MCI™ can also be controlled  
by the LAS (Leica Application Suite) software.  
Maximum brightness  
Maximum contrast  
Point illumination  
from the rear  
Point illumination  
from the left  
Point illumination  
from the right  
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107  
Leica LED5000 RL  
Use  
Using the keyboard  
The illumination scenarios  
Use the " " and " " keys to toggle between the  
illumination scenarios shown below.  
ρ
The Leica LED5000 RL ("Ring Light") generates  
a very bright and homogenous incident light.  
It has a diameter of 80 mm and illuminates the  
specimen with 48 LEDs that can be switched on  
and off completely or in various combinations.  
It is controlled using either the integrated or via  
the Leica Application Suite (LAS).  
Use the key to switch the illumination on  
or off.  
ρ
Use the "+" and "–" keys to adjust the  
brightness in 10 increments. Touch either  
of the two buttons to adjust the intensity in  
small increments. Hold a key to change the  
intensity more quickly.  
Constraint  
The Leica LED5000 RL has been designed for  
use with the 1.0× and 0.63× objectives. For the  
1.6× and 2.0× objectives, conventional ring  
illuminators from the Leica illuminator product  
range are available.  
LAS enables you to create fully reproducible  
illumination scenarios and automatically toggle  
between them. For additional information, refer  
to the LAS online help.  
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108  
 
Leica EL6000 – About the Instrument  
The Leica EL6000 compact light source is  
intended for biological routine and research  
work, including the examination of specimens  
from the human body for the purpose of gain-  
ing information.  
Special features:  
Heat-absorbing filter  
The Leica EL6000 compact light source has an  
automatic beam cover. This ensures that the  
light beam output of the instrument when the  
light guide is detached. This prevents the user  
from being harmed by the intense light beam  
generated by the instrument.  
When the cover is open, the holder for the heat  
filter can be accessed. Here, (hardened) heat-  
absorbing filters for protecting the light guide  
and various conversion filters with a diameter  
of 32 mm for adapting the spectrum to the  
application can be inserted.  
The Leica EL6000 compact light  
source is intended exclusively for  
operating mercury short-arc lamps of type  
HXP-R120W/45C VIS from OSRAM in conjunc-  
tion with a suitable light guide for the instru-  
ment. Any other use of the instrument shall be  
considered noncompliant use.  
The Leica EL6000 compact light source has a  
built-in shutter. It can be operated at the instru-  
ment itself by means of a pushbutton or via a  
remote control input. The shutter is open when  
the "open" LED is illuminated.  
The Leica EL6000 comes factory-equipped with  
a heat-absorbing filter.  
The brightness can be varied in 5 increments  
(0% – 100%). For this purpose, a mechanical  
dimming unit that can be operated using a  
rotary switch on the front of the unit is installed  
in the device.  
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109  
 
Leica EL6000 – About the Instrument (cont'd.)  
Compatible light guides  
Identification of the instrument  
The Leica EL6000 compact light source complies  
with Council Directive 98/79/EC concerning in  
vitro diagnostics. It also conforms to the Coun-  
cil Directives 73/23/EEC concerning electrical  
apparatus and 89/336/EEC concerning electro-  
magnetic compatibility for use in an industrial  
environment.  
The Leica EL6000 compact light source is  
compatible with liquid light guides that are  
compatible with a "Storz long" light inlet and  
whose transmission curve fits the lamp used.  
Where applicable, refer to the lamp's data sheet  
for its spectral light distribution.  
The nameplate of the instrument is on its  
bottom. It includes the necessary information  
for identifying the instrument.  
When connecting the light guide to the light  
source or the microscope adapter, make sure  
not to kink or damage the light guide.  
Your Leica consultant will be glad to provide  
additional information about suitable light  
guides.  
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110  
Leica EL 6000 – Operation  
Controls  
Running-time meter  
Shutter control  
ρ
The running-time meter measures the burn-  
ing time of the lamp, not the switch-on time  
of the Leica EL6000 compact light source. The  
running-time meter displays its current status  
in this format: hours – minutes.  
In the "open" position, the shutter of the  
Leica EL 6000 is open—regardless of the  
signal from the remote control.  
ρ
If the shutter control is in the "remote" posi-  
tion, the shutter is controlled by the remote  
control.  
1. Press the reset button to set the running-  
time meter of the lamp to "0".  
5
The running-time meter should be reset after  
every lamp replacement so that it always  
displays the current, accurate lamp life.  
Intensity switch  
The intensity switch provides optical dimming  
of the light in five fixed increments.  
4
3
2
1
Discontinue using the built-in lamp when it  
reaches the end of the life specified by the  
manufacturer.  
1
2
3
4
5
Power switch/power indicator  
Reset button for running-time meter  
Running-time meter  
Shutter control  
Intensity switch  
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111  
 
Leica EL 6000 – Troubleshooting  
Fault description  
Possible faults  
Remedy  
No power supply voltage present; connecting Check power supply voltage and connecting  
cable not plugged in correctly/defective  
Fuses in instrument defective  
cable  
Power indicator is not illuminated after being  
switched on, instrument shows no function  
Replace fuses, use permitted replacement  
type only (see Page 113)  
Housing cover loose  
or removed  
Attach housing cover securely  
Power switch is illuminated after being switched  
on, instrument shows no function  
Lamp worn out  
Replace lamp  
Shutter closed or intensity switch at left limit  
stop  
Open shutter or rotate intensity switch  
towards the right  
Target system receives too little light or none at all Light guide not inserted into light guide  
output properly  
Check light guide  
Light guide damaged/defective  
Repair or replace  
If these actions do not fix the problem, send the Leica EL6000 compact  
light source to Leica service with an exact description of the malfunction.  
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112  
 
Cleaning and Maintenance  
Before carrying out cleaning tasks,  
switch off the Leica EL6000 compact  
light source.  
Spare parts and accessories  
Permitted replacement fuses  
The only parts of the Leica EL6000 compact  
light source that may be replaced by the user  
are the instrument fuses and the lamp.  
Fuse: 5×20, 2.5 A, slow-blowing, breaking capacity H  
Wickmann Series 181  
www.wickmann.com  
Schurter Series SPT 5×20 www.schurter.ch  
Use only a dry, lint-free cloth for cleaning. When  
cleaning, ensure that no dust or other foreign  
bodies enter the device through the ventilation  
slots.  
The replacement of the lamp is described  
on Page 61.  
Repairs  
Opening or working on the Leica EL6000  
compact light source in any manner other than  
described above (changing lamps, changing  
fuses) may be carried out by the supplier of the  
instrument or the supplier's authorized repre-  
sentatives.  
Replacing the instrument fuse  
1. Disconnect the Leica EL6000 from the  
power supply.  
In case of damage (even external damage),  
immediately stop using the Leica EL6000  
compact light source and send it to service.  
2. Open the drawer with the instrument fuses  
located close to the power supply input.  
If it will not be used for a long time, protect the  
Leica EL6000 compact light source from dust  
using a suitable cover (such as the plastic bag  
from the original packaging).  
3. Replace the instrument fuse.  
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113  
 
Fluorescence  
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114  
 
Filter Changer  
The patented FLUOIII® filter system consists of  
a filter changer for barrier and excitation filters,  
a UV shutter that can be activated/deactivated,  
and a filter insert for a filter holder with your  
choice of filter.  
If you are using fewer than four filter  
holders with fluorescence filters, always  
The simple filter holders also protect the  
system from dust.  
insert the included simple filter holders with  
closed illumination beam path into the avail-  
able positions. Otherwise, there is a risk of  
danger to the eyes from direct UV radiation  
from the third beam path.  
Filter sets for fluorescence  
The filter sets for fluorescence contain, on one  
filter holder, two barrier filters to the visual  
beam paths and one excitation filter to the illu-  
mination beam path. The fluorescence filters  
have a transponder with the specific filter data  
for use with the motorized Leica M205 FA. The  
filter sets are labeled (see Page 118).  
The filter changer can hold a total of 4 filter sets.  
The filter sets for fluorescence are labeled (see  
Page 118). All filter sets are equipped with a tran-  
sponder for automatic filter detection and can  
also be used with the motorized Leica M205 FA.  
The scope of delivery of the Leica M205 FA and  
Leica M165 FC includes three simple filter hold-  
ers without fluorescence for empty filter posi-  
tions and transmitted or incident light observa-  
tion without fluorescence. These filter holders  
have two empty openings for the observation  
beam paths. The third opening, to the illumina-  
tion beam path, is closed.  
A selection of the available filters  
including simple filter holder (bottom right)  
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115  
 
FIM – Fluorescence Intensity Manager  
FIM consists of a diaphragm disk with pinhole  
diaphragms of varying transmission capaci-  
ties. The intensity of the excitation light can  
be reduced in five fixed steps. The light can  
be changed from 100% to 55%, 30% and 17%  
down to 10%.  
The advantage of this procedure is its absolute  
reproducibility and fast switching between the  
intensity levels. A separate FIM level can be  
stored for every fluorescence filter. Different  
intensities of fluorescence can thus be cali-  
brated to one another.  
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116  
 
About Fluorescence Microscopy  
Functional principle  
The Leica M Series  
The filter system  
Fluorescent substances light up when irradi-  
ated with short-wave excitation light, and fluo-  
rescence microscopy takes advantage of this  
property. Specimens without self-fluorescence  
are stained with a fluorescent substance. One  
such dye is green fluorescent protein (GFP),  
which is used in molecular biology.  
The Leica M series fluorescence stereomicro-  
scopes allow entire fluorescent specimens to  
be studied, unprepared and in three dimen-  
sions. The fully apochromatic optics system and  
the enormous zoom range make the Leica M  
series stereomicroscopes your first choice. The  
patented TripleBeam® third beam path for fluo-  
rescence illumination and the patented FLUOIII®  
filter system generate highest-quality fluores-  
cence images. The very bright high-pressure  
mercury burner and specially selected filter sets  
enable you to distinguish the finest structures  
and enhance the quantity of information for  
incident light fluorescence.  
The FLUOIII® filter system consists of a rapid  
filter changer for barrier and excitation filters  
and a filter insert for a filter holder with your  
choice of filter. A total of four filter sets (which  
are labeled) can be used in the rapid filter  
changer. An empty filter cartridge is also avail-  
able for individual filter combinations. Each  
filter set includes two barrier filters to the visual  
beam paths and an excitation filter to the illu-  
mination beam path.  
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117  
 
Rapid Filter Changers and Filter Types  
The rapid filter changer must be equipped with four filter holders at all times.  
Filter sets  
GFP  
Excitation filter  
Barrier filter  
Designation  
425/60 nm (395–455 nm)  
480/40 nm (460–500 nm)  
470/40 nm (450–490 nm)  
360/40 nm (340–380 nm)  
425/40 nm (405–445 nm)  
470/40 nm (450–490 nm)  
546/10 nm (541–551 nm)  
436/20 nm (426–446 nm)  
510/20 nm (500–520 nm)  
560/40 nm (540–580 nm)  
545/30 nm (510–560 nm)  
620/60 nm (590–650 nm)  
555/60 nm (530–580 nm)  
480 LP  
GFP1  
GFP2  
GFP3  
UV  
GFP Plus  
GFP plants  
UV  
510 LP  
525/50 nm (500–550 nm)  
420 LP  
Violet  
Blue  
460 LP  
V
515 LP  
B
Green  
CFP  
590 LP  
G
480/40 nm (460–500 nm)  
560/40 nm (540–580 nm)  
610 LP  
CFP  
YFP  
TXR  
DSR  
CY5  
CY3  
YFP  
Texas Red  
DsRED  
CY5  
620/60 nm (590–650 nm)  
700/75 nm (663–737 nm)  
610/75 nm (573–648 nm)  
CY3  
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118  
 
Simple filter holders  
Simple filter holders  
Safety Notes  
If you are using fewer than four filter  
holders with fluorescence filters, always  
ρ
Three simple filter holders are included with  
the Leica M165 FC and the Leica M205FA. These  
filter holders have two empty openings for the  
observation beam paths. The third opening, to  
the illumination beam path, is closed.  
If you want to block the mercury light for  
longer than that, activate the UV shutter.  
insert the included simple filter holders with  
closed illumination beam path into the avail-  
able positions. Otherwise, there is a risk of  
danger to the eyes from direct UV radiation  
from the third beam path.  
ρ
ρ
Use the filter if you want to change to trans-  
mitted light or incident light observation  
without fluorescence.  
ρ
Use this filter holder if you want to work  
briefly (no more than 15 seconds) without  
fluorescence illumination.  
Always place a simple filter holder into the  
empty filter changer positions in order to  
protect yourself from UV radiation and  
protect the system from dust.  
So that the filter holder is not heated,  
it must not block the mercury light for  
longer than 15 seconds.  
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119  
 
Equipping the Filter Changer  
When inserting the filter sets, avoid  
Removing the simple filter holder  
Inserting the filter  
touching the filters in order to avoid  
fingerprints. Clean dirty filters immediately  
using a soft, lint-free cloth and pure alcohol.  
The Leica M165 FC and the Leica M205FA are  
equipped at the factory with simple filter hold-  
ers as "dummies". These must be removed  
before inserting a filter.  
1. Place the filter into the filter changer.  
Ensure that the contour of the filter holder  
matches the contour of the microscope.  
1. Grasp the recess of the dummy in the filter  
changer and pull it out.  
2. Rotate the filter changer by hand until it  
latches into place.  
If the filter holder has not been inserted  
correctly, the filter changer does not rotate.  
3. Insert a total of four filters.  
Slot for filter slide  
There is a slot in the filter changer system for  
an individually selectable filter, for example a  
neutral density filter.  
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120  
 
Observation without Fluorescence  
We recommend that you first familiarize  
yourself with the controls of your Leica  
fluorescence microscope in transmitted light  
without the presence of fluorescence illumina-  
tion.  
Observation without Fluorescence  
Close the UV shutter when you do not want to  
view the specimen with fluorescence illumina-  
tion, but only with transmitted light.  
The FLUOIII® filter system includes a UV shutter  
that can be used to close the illumination beam  
path. This feature protects the mercury lamp,  
which should not be switched on and off too  
frequently. If, for instance, you need to inter-  
rupt your work, you do not have to switch off  
the high-pressure mercury burner to preserve  
sensitive specimens from being burned out or  
bleached out.  
After switching on the high-pressure  
mercury burner, you must adjust the arc  
lamp immediately (see User Manual M2-216-1).  
We recommend that you first familiarize  
yourself with the basic functions of your  
Leica stereomicroscope as they are described in  
the previous section of this User Manual. These  
include the binocular tube, the eyepieces, the  
zoom magnification changer, the focusing  
drive, and others.  
Switching the high-pressure mercury  
burner on and off frequently decreases  
its life and causes delays, as the lamp can only  
be switched back on after it has cooled. Instead,  
you can close the UV shutter and reopen it  
when you return to your workplace.  
The following describes the specific functions  
of the fluorescence system only.  
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Leica M-series  
121  
 
Double Iris Aperture  
The built-in double-iris diaphragm regulates  
the depth of field. Note that:  
ρ
The greater the depth of field, the darker  
the image becomes.  
ρ
In the same way, the exposure time  
becomes longer for photographs.  
ρ
The resolution decreases.  
Adjusting the double-iris diaphragm using the  
knurled ring  
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Leica M-series  
122  
 
Commissioning the Fluorescence System  
After switching on the high-pressure mercury  
burner, you must adjust the arc lamp imme-  
diately (see User Manual M2-216-1). Do not  
switch on the supply unit until you feel confi-  
dent using the Leica stereomicroscope.  
For observation with fluorescence light,  
always position the protection screen  
correctly to protect the observer (see Page 27).  
Follow all safety instructions when  
handling mercury lamps and the lamp  
housing!  
1. Switch on the supply unit (see User Manual  
M2-216-1).  
2. Wait 2–3 minutes.  
3. Adjust the arc lamp in accordance with User  
Manual M2-216-1.  
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Leica M-series  
123  
 
Accessories  
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Leica M-series  
124  
 
Leica SmartMove  
With its non-slip controllers and knobs, the  
Leica SmartMove control unit offers the right  
feel for handling motorized Leica instruments.  
Controls  
The functions of the individual controls can be  
configured both directly on the Leica Smart-  
Move and using the Leica Application Suite.  
For a detailed description of the functions and  
settings, please refer to the Leica SmartMove  
manual or the Leica Application Suite help file.  
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Leica M-series  
User Manual  
125  
 
Leica SmartTouch™  
ρ
ρ
ρ
ith the touchscreen of the Leica SmartTouch™,  
an control your experiment procedures  
a few hand movements and never lose  
of all your important optical parameters.  
Top part of the knob = zoom  
Upper part of the knob = focus  
Buttons = left filter, right filter, shutter  
most important control functions on the  
ol unit can be adjusted to your specific  
with freely programmable rotary knobs  
nction buttons.  
For a detailed description of the functions and  
settings, please refer to the Leica SmartTouch™  
manual or the Leica Application Suite help file.  
ols  
unctions of the individual knobs and  
n elements can be configured both directly  
e Leica SmartTouch™ and using the Leica  
ation Suite.  
andard configuration when shipped from  
the factory is as follows:  
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Leica M-series  
126  
 
Leica PSC Controller  
Use  
Passing over the specimen quickly  
Control by LAS  
ρ
The Leica PSC controller gives you precision  
control of the Leica IsoPro™ motorized mechan-  
ical stage.  
Move the joystick in any desired direc-  
The instructions for controlling the Leica IsoPro™  
using the Leica Application Suite are provided  
in the software's help file.  
tion (including diagonally) to control the  
mechanical stage quickly.  
Connection  
Connect the Leica PSC controller and the Leica  
IsoPro™ motorized mechanical stage to the  
DCI box.  
Fine control of the mechanical stage  
The motorized Leica IsoPro™ mechanical stage  
offers an accuracy of up to 0.25 µm. To move to  
a position with maximum accuracy, use the left  
and right knobs on the joystick.  
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Leica M-series  
127  
 
Dimensional Drawings  
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Leica M-series  
User Manual  
128  
 
Leica M165 FC  
Leica M165 FC with incident light base and new focusing column  
(dimensions in mm)  
292  
217  
154  
154  
340  
385  
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Leica M-series  
User Manual  
129  
 
Leica M165 FC (cont'd.)  
Leica M165 C with TL RCI™ transmitted light stand, Leica IsoPro™ manual mechanical stage and manual focusing drive  
292  
217  
154  
187  
497  
X = +-75 mm  
370  
max. 370  
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Leica M-series  
130  
Leica M165 FC (cont'd.)  
Leica M165 C with TL RCI™ transmitted light stand and manual focus  
292  
217  
154  
154  
340  
356  
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Leica M-series  
User Manual  
131  
Leica M205 FA  
Leica M205 FA with TL BFDF transmitted light stand, ErgoTrinoc tube, DFC camera and motorized focusing drive  
292  
340  
154  
154  
370  
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Leica M-series  
132  
 
Leica M205 FA (cont'd.)  
Leica M205 FA with TL RCI™ transmitted light stand, ErgoTrinoc tube, DFC camera and motorized focusing drive  
292  
340  
154  
154  
385  
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Leica M-series  
133  
Leica M205 FA (cont'd.)  
Dimensions of Leica M205 FA with TL RCI™ transmitted light stand, IsoPro™ mechanical stage, ErgoTrinoc tube, DFC camera and motorized  
focusing drive  
292  
154  
187  
497  
X = +-75 mm  
370  
max. 410  
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Leica M-series  
134  
Leica LED5000 MCI  
Leica LED5000 MCI  
(dimensions in mm)  
132  
275.3  
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Leica M-series  
135  
 
Leica LED5000 RL  
30  
ø70  
120  
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Leica M-series  
User Manual  
136  
 
MATS TL  
11  
140  
190  
220  
4
10 447 275  
10 447 164  
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Leica M-series  
137  
 
Specifications  
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Leica M-series  
138  
 
Leica M165 FC / Leica M205 FA  
Leica M165 FC  
Leica M205 FA  
Optical data  
Zoom  
16.5 : 1 manual  
20.5 : 1 automated with FusionOptics™  
Data with standard optics (1×objec-  
tive/10× eyepieces)  
– Zoom range  
7.3×–120×  
max. 453 lp/mm  
61.5 mm (planapochromat)  
31.5 mm – 1.92 mm  
7.8×–160×  
max. 525 lp/mm  
61.5 mm (planapochromat)  
29.5 mm – 1.44 mm  
– Resolution  
– Working distance  
– Object field  
Maximum values (based on optics combi-  
nation)  
– Magnification  
960×  
1280×  
906 lp / mm  
551 nm  
0.302  
1050 lp / mm  
476 nm  
0.35  
– Resolution  
– Visible structural width  
– Numerical aperture  
– Object field  
63 mm  
59 mm  
Working distances  
135 mm (0.5× planachromat)  
112 mm (0.8× planachromat)  
67 mm (0.63× planapochromat)  
61.5 mm (1× planapochromat)  
30.5 mm (1.6× planapochromat)  
20.1 mm (2× planapochromat)  
135 mm (0.5× planachromat)  
112 mm (0.8× planachromat)  
67 mm (0.63× planapochromat)  
61.5 mm (1× planapochromat)  
30.5 mm (1.6× planapochromat)  
20.1 mm (2× planapochromat)  
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Leica M-series  
139  
 
Leica M165 FC / Leica M205 FA (cont’d.)  
Leica M165 FC  
Leica M205 FA  
Optics carrier  
100% apochromatic optical system  
CMO (Common Main Objective) lead-free  
CMO (Common Main Objective) lead-free  
Specific surface resistivity  
(housing)  
2×1011 Ω/mm2  
discharge time <2 seconds from 1000V to 100V  
2×1011 Ω/mm2  
discharge time <2 seconds from 1000V to 100V  
Encoded/automated (M205 FA)  
Zoom, iris diaphragm, objective nosepiece  
Zoom, iris diaphragm, objective nosepiece,  
FIM, filter  
Engageable zoom notches  
13 for repetitive tasks  
Built-in and encoded  
14 for repetitive tasks  
Built-in and motorized  
Double-iris diaphragm for depth of field  
control  
FIM ( Fluorescence Intensity Control )  
Built-in and motorized  
1× planapochromat  
Accessories  
Standard objective (parfocal in the objec-  
tive nosepiece)  
1× planapochromat  
Additional objectives (parfocal in the  
objective nosepiece)  
5× planachromat, 2× planapochromat, 1.6×  
planapochromat, 0.63× planapochromat  
5× planachromat, 2× planapochromat, 1.6×  
planapochromat, 0.63× planapochromat  
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Leica M-series  
140  
Leica M165 FC / Leica M205 FA (cont’d.)  
Leica M165 FC  
Leica M205 FA  
Additional objectives (non-parfocal)  
Interpupillary distance  
1× planachromat, 0.8× planapochromat, 0.63×  
planapochromat, 0.5× planapochromat  
1× planachromat, 0.8× planapochromat, 0.63×  
planapochromat, 0.5× planapochromat  
50 mm–105 mm  
50 mm–105 mm  
Wide-field eyepieces for persons wearing  
glasses  
10×, 16×, 25×, 40×, with replaceable  
eyecups & click stop  
10×, 16×, 25×, 40×, with replaceable  
eyecups & click stop  
Manual coarse/fine focus  
Motorized focusing drive  
Focusing range 130 mm,  
adjustable ease of movement  
Focusing range 130 mm,  
adjustable ease of movement  
Motorized focusing drive with 431 mm profile  
column, with power supply  
Motorized focusing drive with 431 mm profile  
column, with power supply  
Computer interface  
USB  
USB  
Module System  
Stands, illuminators  
Transmitted light stands  
For bright field and bright/dark field, high-performance base: Bright field, single-sided dark field,  
with Rottermann Contrast and CCIC  
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141  
Leica M165 FC / Leica M205 FA (cont’d.)  
Leica M165 FC  
Leica M205 FA  
Incident light stand  
Stages  
Large incident light base with black/white stage plate and Antishock™ feet  
Gliding stage, MATS heating stage, cup stage, rotatable polarization stage,  
Leica IsoPro™ mechanical stage (manual and motorized)  
Illuminators  
LED5000 MCI™ and LED5000 RL, fluorescence, oblique, coaxial, cold light sources  
Misc. accessories  
Photography, video  
– Leica DFC digital image capture system, various camera variants, Leica IC D  
– Leica IC A video module  
– Various adapters for commercially available CCD cameras  
Image archiving, image processing  
Leica AF6000: Special software for all fluorescence tasks  
Leica Application Suite (LAS): consisting of basic program and various auxiliary modules  
Measurement graticules  
Vertical and oblique observation  
Drawing tube  
For length measurements and counting  
45° side view around the complete object  
For both left and right-handed users  
For detailed information about optical accessories, binocular tubes, stands, illuminators  
and additional accessory modules for various applications, refer to the brochure  
"Leica M Stereomicroscopes – The Modular System", M1-105-4en.  
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142  
Leica EL6000 – Specifications  
Dimensions (W×H×D)  
Width×height×depth  
Electrical safety  
in accordance with EN 61010-1:2001  
Pollution degree  
130 mm × 210 mm × 290 mm  
Environmental conditions  
Permitted ambient temperature  
Permitted relative humidity  
2
II  
-20 to 85 °C  
Overvoltage category  
Power input  
Design  
10% to 90%,  
non-condensing  
Switched socket IEC320 C13  
(EN 60320 C13)  
Operation  
Permitted ambient temperature  
Permitted relative humidity  
Operational data  
Application area  
0 to 40 °C  
Power supply voltage  
Power frequency  
100 to 240 VAC ( 10%)  
50 to 60 Hz  
10% to 90%, non-condensing  
Fuse protection  
2x T2.5 A; Breaking capacity  
H (manufacturer: Wickmann;  
Series 181)  
Enclosed rooms  
Altitude for use  
Max. 2000 m above sea level  
Protective class  
I
Power consumption  
Max. 210 VA  
Type of protection  
EMC  
Emitted interference  
Immunity to interference  
Voltage fluctuations, flicker  
Harmonic currents  
IP20 (EN 60529)  
Lamp  
Type  
Mercury short-arc reflector  
lamp  
EN 61326 (Class B)  
EN 61326 Appendix A  
EN 61000-3-3  
Designation  
OSRAM HXP-R120W/45C VIS  
120 W  
Power consumption  
EN 61000-3-2  
Service life (manufacturer information) Average value 2000 h  
The instrument fulfills the requirements of EC Directive 89/336/EEC and  
the EMC law of September 18, 1998  
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143  
 
Leica EL6000 – Specifications (cont'd.)  
Light output  
Protective functions  
Design  
Type: Storz, long  
Safety circuit  
If the cover is open, all components in the instru-  
ment (except for the power input and power plug)  
are disconnected from the power supply voltage.  
In the event of overheating, the lamp supply is shut  
off. After cooling off, the lamp power supply in the  
Leica EL6000 compact light source is automatically  
switched on again.  
Special feature  
Self-locking if no light guide is  
plugged in  
Overheating  
protection  
Fan  
Switch-on delay  
Approx. 60 s after lighting the  
lamp  
Interface  
Protection screen If no light guide is plugged into the light output of  
the instrument, the light output is automatically  
closed off so that no light can escape.  
Type  
Remote control input for  
internal shutter  
Design  
9-pin D-Sub socket  
Remote signal level  
– Shutter closed  
– Shutter open  
– Input current  
Footswitch  
–8 to +0.8 V  
+2.4 to +8 V  
Approx. 1 mA  
– Shutter closed  
Connection between  
pin 2 and 4  
– Current  
Approx. 1.2 mA  
Max. 10 Hz  
Shutter frequency  
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Leica M-series  
144  
Leica TL ST Transmitted-light Base  
Light source  
Halogen lamp 12V/20W  
Quick illuminant change  
Illuminated area  
Power supply unit  
Yes  
50 mm  
Input voltage 100–240 V~, frequency 50–60 Hz  
energy consumption 30 W max.,  
ambient temperature 10 – 40 °C  
Power plug, power switch  
7.4 kg  
Connections  
Weight  
Illumination types  
Bright field  
Yes  
Dark field  
Yes (single-sided)  
Oblique light  
No  
No  
Relief Contrast System (RC™)  
CCIC (Constant Color Intensity Control) No  
Internal shutter/lamp control  
Integrated filter holder  
Coated optics for increasing the color  
temperature  
No  
Yes  
Yes  
Matching of high num. aperture  
Remote control options  
AntiShock™ Pads  
No  
No  
Yes  
Dimensions (W×H×D)  
340×430×85 mm  
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145  
 
Leica TL BFDF Transmitted-light Base  
Light source  
External via cold light source  
Illuminated area  
Connections  
40 mm  
Connection for cold light guide,  
active f=10mm, end tube f=13mm  
5.8 kg  
Weight  
Illumination types  
Bright field  
Yes  
Yes  
No  
No  
Dark field  
Oblique light  
Relief Contrast System (RC™)  
CCIC (Constant Color Intensity Control) No  
Internal shutter/lamp control  
Integrated filter holder  
Coated optics for increasing the color  
temperature  
Yes*  
No  
No  
Matching of high num. aperture  
Remote control options  
AntiShock™ Pads  
Yes**  
Yes***  
Yes  
Dimensions (W×H×D)  
340×390×90 mm  
*With cold light source Leica CLS150 LS **Concave mirror *** With external light source  
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146  
 
Leica TL RC™ / TL RCI™  
Leica TL RC™  
Leica TL RCI™  
Light source  
External via cold light source  
Halogen lamp 12V/20W  
Yes  
Quick illuminant change  
Illuminated area  
Power supply unit  
35 mm  
35 mm  
100–240 V~, frequency 50–60 Hz  
energy consumption 30 W max.,  
ambient temperature 10 – 40 °C  
1×USB type A, 1×USB type B, 2×CAN-BUS  
Connections  
Weight  
Connection for cold light guide,  
active f=10mm, end tube f=13mm  
6.0 kg  
7.2 kg  
Illumination types  
Bright field/dark field  
Yes/yes  
Yes/yes  
No  
Yes/yes  
Oblique light/Relief Contrast System (RC™)  
CCIC (Constant Color Intensity Control)  
Internal shutter/lamp control  
Integrated filter holder  
Yes/yes  
Yes  
Yes**  
Yes  
Yes  
Yes  
Coated optics for increasing the color temperature  
Matching of high num. aperture  
Remote control options  
Yes  
Yes  
Yes***  
Yes****  
Yes  
Yes***  
Yes  
AntiShock™ Pads  
Yes  
Dimensions of base (W×H×D)  
340×390×95 mm  
340×440×95 mm  
*Single-sided **With cold light source Leica CLS150 LS ***Concave mirror ****With external light source  
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Leica M-series  
147  
 
Leica IsoPro™ Motorized XY Stage  
Compatibility  
Stage size (L ×W × H)  
Travel  
Leica incident light base and TL bases (TL BFDF, TL RC™, TL RCI™)  
335.5 mm × 370 mm × 41.5 mm  
152 mm × 102 mm (6" × 4")  
Speed X,Y  
30 mm/s  
Motor resolution X,Y  
Repeatability X,Y  
Positioning accuracy X,Y  
Hysteresis X, Y  
Motor  
0.25 µm  
2 µm  
20 µm over the entire positioning range  
30 µm  
Direct current (DC) motor with encoder  
Backlash  
Slack-free  
Adapter  
All adapters for TL bases  
Acceleration  
S-shaped acceleration  
Computer connection  
Control options  
Power supply  
USB  
Leica PSC™, Leica Smart Move, Leica SmartTouch™, Leica LAS via PC  
Input: 100–240VAC 50 / 60 Hz 1.0 A  
Output: 15 VDC 2.66 A 40W max.  
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User Manual  
148  
 
Appendix  
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Leica M-series  
149  
 
Calculating the Total Magnification and Field of View Diameter  
Parameter  
Example  
MO  
ME  
z
Magnification of the objective  
MO  
ME  
z
1× objective  
Magnification of the eyepiece  
25×/9.5 eyepiece  
Magnification of the changer position  
Zoom position 4  
q
Tube factor, e.g. 1.5× for coaxial incident light, 1.6× for 45°  
ErgoTube™  
q
Coaxial reflected light 1.5×, tube factor  
Factor 1.25×  
r
r
Factor 1.25x if the planachromatic and planapochromatic  
objectives of the MZ125/MZ16 are used on the MS5, MZ6,  
MZ75 or MZ95  
NFOV Field number of the eyepiece. Field numbers are printed on the  
eyepieces: 10× = 21, 16× = 14, 25× = 9.5, 40× = 6.  
Calculation example: Magnification in the binocular tube:  
Calculation example: Field of view diameter in the specimen  
MTOT VIS = MO × ME × z × q × r  
or  
1 × 25 × 4 × 1.5 × 1.25 = 187.5×  
N
FOV  
OF:  
M
O × z ×q ×r  
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150  
 
Care, Maintenance, Contact Persons  
We hope you enjoy using your high-perfor-  
mance microscope. Leica microscopes are  
renowned for their robustness and long service  
life. Observing the following care and clean-  
ing tips will ensure that even after years and  
decades, your Leica microscope will continue to  
work as well as it did on the very first day.  
Contact address  
Care  
ρ
However, if your instrument should no longer  
function properly, contact your technician,  
your Leica representative or Leica Microsystems  
(Switzerland) AG, CH-9435 Heerbrugg.  
Protect your microscope from moisture,  
fumes and acids and from alkaline, caustic  
and corrosive materials and keep chemicals  
away from the instruments.  
ρ
Plugs, optical systems and mechanical parts  
must not be disassembled or replaced,  
unless doing so is specifically permitted  
and described in this manual.  
E-mail contact:  
Warranty benefits  
The warranty covers all faults in materials  
and manufacture. It does not, however, cover  
damage resulting from careless or improper  
handling.  
ρ
ρ
Protect your microscope from oil and  
grease.  
Do not grease guide surfaces or mechani-  
cal parts.  
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151  
 
Care, Maintenance, Contact Persons (cont'd.)  
Protection from dirt  
Dust and dirt will affect the quality of your  
results.  
Cleaning polymer components  
Permitted measures  
ρ
Some components are made of polymer or are  
polymer-coated. They are, therefore, pleasant  
and convenient to handle. The use of unsuitable  
cleaning agents and techniques can damage  
polymers.  
Clean the microscope (or parts of it) using  
warm soapy water, then wipe using distilled  
water.  
ρ
Put a dust cover over the microscope when  
ρ
it will not be used for a long time.  
For stubborn dirt, you can also use ethanol  
(industrial alcohol) or isopropanol. When  
doing so, follow the corresponding safety  
instructions.  
ρ
Use dust caps to protect tube openings,  
tubes without eyepieces, and eyepieces.  
ρ
ρ
Keep accessories in a dust-free place when  
Remove dust with a pneumatic rubber bulb  
not in use.  
or with a soft brush.  
ρ
Clean objectives and eyepieces with  
special optic cleaning cloths and with pure  
alcohol.  
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152  

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