EN-p2-20-(NE-U22)-3 3/25/02 4:48 PM Page 1
I N S T R U C T I O N M A N U A L
MESH NEBULIZER
Model
NE-U22
Before Using the Unit
Notes on Safety. . . . . . . . . . . . . . . . . . . . . 2
Product Features. . . . . . . . . . . . . . . . . . . . 5
Product Contents. . . . . . . . . . . . . . . . . . . . 5
Names and Functions of the Parts . . . . . . 6
How to Assemble the Main Unit. . . . . . . . . 8
Correct Use of the Unit
How to Prepare the Power Source . . . . . 10
How to Fill the Medication . . . . . . . . . . . . 12
How to Select the Nebulization Mode . . . 14
How to Inhale. . . . . . . . . . . . . . . . . . . . . . 15
How to Clean the Unit after Inhalation. . . 16
How to Disinfect the Unit
Thank you very much for purchasing
OMRON Mesh Nebulizer.
How to Disinfect. . . . . . . . . . . . . . . . . . . . 18
How to Replace the Mesh Cap . . . . . . . . 19
Troubleshooting
Be sure to read this Instruction Manual
before using the unit for you to use it
safely and correctly.
How to Carry the Unit . . . . . . . . . . . . . . . 20
Troubleshooting. . . . . . . . . . . . . . . . . . . . 21
Specifications / Option parts . . . . . . . . . . 22
Keep this Instruction Manual always at
hand for your future reference.
This unit is a medical instrument. Be sure to follow the instructions of a doctor and use the unit correctly.
For the type, dose, and regimen of medication, be sure to follow the instructions of a doctor.
This unit is not appropriate to use as a household inhalator for humidifying the mucous membranes of throat and nose.
The nebulization characteristics of this unit differ by the properties of medication. Especially with the use of a medication
having high surface activity or viscosity such as medication solubilizing agent or expectorant, the nebulization rate may be
reduced. The nebulization rate may also be reduced when the temperature of medication is low.
This unit cannot nebulize distilled water.
The electromagnetic compatibility of this unit conforms to the Medical
Electric Instrument EMC Standard IEC60601-1-2 (1993 version).
The illustrations in this Instruction Manual are image drawings.
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Product Features
Newly developed alloy mesh and titanium vibrator
1 Superior mesh technology that improves nebulization
efficiency.
Pocket-sized unit.
2
As the unit is small enough to be placed in the pocket, you can easily carry it
around wherever you go.
Inhalation possible at various tilt angles.
3
The new bottle structure enables inhalation at various tilt angles.
Nebulization remains stable even when the unit is tilted.
Product Contents
Please check the product.
The following items are contained in the box. If any item is missing, please contact the
store where you purchased the product or the nearest OMRON dealer.
1. Main Unit
Cover
2. Main Unit
3. Medication 4. Mesh Cap
Bottle (with Mesh)
5. Mask
Adapter
9. Storage bag
6. Mouthpiece 7. Inhalation Mask (S) 8.Inhalation Mask (L)
(with rubber string) (with rubber string)
10. Instruction Manual
To start inhalation, you must assemble the unit.
Please read the section on “How to Assemble the Main Unit” and
understand the points for assembling before starting to use the unit.
(Refer to Pages 6 and 7.)
3
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Names and Functions of the Parts
Mesh Cap
An alloy mesh is installed for
nebulization.
- Mesh Cap is consumable.
Mesh Cap Cover
Protects the Mesh.
A figure viewed
from the above
Medication Port
Fill the medication by
opening the Mesh Cap.
Vibrator
The tip of this Vibrator
vibrates at high frequency
and pushes out medication
from the pores of Mesh.
Electrode
A contact point connecting
the Main Unit and the
Medication Bottle.
Battery Low Indicator
An orange light flashes
when the batteries are worn.
Main Unit Cover
Used for storing or
carrying the unit.
Button
Turns on and off the power
with a push of the Button.
Battery Cover
Battery Cover
Disengaging Lever
Opens and closes
the Battery Cover.
AC Adapter Jack
to Electrode
Connects the Main
Unit and AC Adapter.
A figure viewed
from the rear
4
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Nebulization Port
Nebulize medication here.
Do not insert your
finger into the
Nebulization Port.
A figure viewed
from the rear
Mesh
Efficient nebulization is realized from the minute pores.
- Mesh is an extremely minute part. Handle it carefully.
Air Port
Stabilizes nebulization.
Medication Bottle Cap Locking Lever
Opens the Medication Bottle Cap.
- Do not open Medication Bottle Cap except
when washing Medication Bottle.
Medication Bottle Cap
Medication Bottle
Stores the medication.
Medication Bottle Disengaging Button
Medication Bottle can be removed when the Buttons
on both sides of the Medication Bottle are pressed.
Electrode
Connects the Main Unit and the Power Source.
A figure viewed
from the rear
Power Indicator
A green lamp turns on when the power is on.
AC Adapter as Optional Supply
Cord Band
AC Adapter
Power Plug*
Electrode
Supplies the power
to the Main Unit.
Main Unit
Locking Board
* Actual power plug may not be
the same as illustration.
AC Adapter Connection Stand
5
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How to Assemble the Main Unit
First, check how to assemble the unit.
You must assemble the unit before starting to use it.
You may find the parts slightly hard to assemble because they are made to
prevent the medication from leaking.
Be sure to clean and disinfect the unit before using. Dry the unit after cleaning
and disinfecting.
(Refer to Pages 14 to 16.)
1 Install the Mesh Cap on the Medication Bottle.
- Do not insert the Mesh Cap in the opposite direction.
Insert the Mesh Cap
perpendicular to the
Medication Bottle.
Installation is
complete.
Align these points.
Securely close the
Mesh Cap and the
Medication Bottle.
Do not insert your
finger into the
Nebulization Port.
Do not open
the Bottle Cap.
2 Install the Medication Bottle to the Main Unit.
Installation is
complete.
Align both
Electrodes with
each other.
Install the Medication
Bottle to the Main Unit.
- If carrying the unit after the Medication Bottle is installed,
hold on the Main Unit. Do not hold on the Medication Bottle.
6
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Installation is
complete.
3 Install the Mask Adapter
to the Main Unit.
Securely cover the
Main Unit with the
Mask Adapter.
Install the Mouthpiece or
the Inhalation Mask (S) or
(L) to the Mask Adapter.
I How to install the Inhalation Mask (S)
I How to install the Mouthpiece
Installation is
complete.
Installation is
complete.
Insert the
Mouthpiece
as far as it
goes.
End of the
Mouthpiece
with larger
diameter is
on the top.
Insert the
Inhalation
Mask as far
as it goes.
If you are not going to use the unit soon after it is
assembled.
Remove the supplied Mask Adapter and Mouthpiece,
or Inhalation Mask as shown in the Figure.
Store the unit in the supplied Storage Bag or in a
clean place.
To remove the Medication
Bottle from the Main Unit
To removie the Mesh Cap from
the Medication Bottle
Do not insert your
finger into the
Nebulization Port.
7
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How to Prepare the Power Source
Connect the unit to the power source before starting to use it.
Use batteries or optional AC Adapter as the power source.
How to use the optional AC Adapter
Please note that this AC Adapter is not a battery charger.
1 Place the Main Unit on the AC Adapter
Connection Stand as shown in the Figure.
Main Unit Locking Board
- Push in the AC Adapter until it clicks
and is locked to the Stand.
2 Plug in the power plug of AC Adapter to the electric outlet.
Connection is completed.
How to remove the AC Adapter from the Main Unit
(1) Unplug the power plug from the
(1) Unplug
electric outlet.
(2) Unlock the Main Unit by pushing in
both ends of the Main Unit Locking
Board of the AC Adapter Connection
Stand with your fingers.
(2) Push both ends to
remove the Main Unit.
Main Unit Locking Board
8
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How to Insert Batteries
Batteries are not supplied. Use two commercially available AA alkaline batteries. You can also use
nickel-hydrogen batteries (rechargeable batteries). If you use a commercially available battery charger,
you can save cost by recharging the batteries repeatedly.
(2)
1 Remove the Battery Cover.
Bottom of the
Main Unit
(1) Slightly rotate the Battery Cover
Disengage Lever in the direction of
the arrow, and
(1)
(2) Remove the Battery Cover.
- The Battery Cover may not be removed easily when the
batteries are not inserted.
2 Insert batteries correctly by
aligning the polarities (+ and -)
with the battery indication mark.
3 Put on the Battery Cover.
Put the Battery Cover on the Battery Case,
and push it in until it catches the claws and
clicks. Push both ends firmly.
- You may find it difficult to push in because the unit is
made to prevent water dropping inside the unit.
Battery life and battery replacement
I When using alkaline batteries
I When using nickel-hydrogen batteries
The unit can be used for approximately 8 days
(if it is used for 30 minutes a day).
The unit can be used for approximately 8 days
(if it is used for 30 minutes a day with the
batteries fully charged.
When the Battery Low Indicator (orange)
flashes, batteries will be worn out soon.
Replace both batteries with new ones.
When the Battery Low Indicator (orange)
flashes, the rechargeable batteries have little
residual power. As the unit does not nebulize,
immediately recharge the batteries with a
commercially available charger.
When the Battery Low Indicator
(orange) turns on, batteries are
worn out. As the unit will not
nebulize, immediately replace
both batteries with new ones.
- The optional AC Adapter does not function
as a battery charger. Use a commercially
available battery charger suitable for the
batteries you are using.
- You may use manganese
batteries. However,
manganese batteries tend to
have a shorter life.
General advice
- Immediately replace the worn batteries with new ones.
- If you are not going to use the unit for a long period of time (3 months or more), remove the batteries or
rechargeable batteries. If you leave the unit without using while keeping the batteries or rechargeable
batteries in it, the batteries may leak and cause trouble to the unit.
- Do not use the batteries other than the ones specified for the unit. Do not use worn and new batteries
together or different types of batteries together.
- Do not insert batteries with the polarities (+ and -) in the wrong direction.
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How to Fill the Medication
Remove the Mask Adapter, Mouthpiece, or Inhalation Mask (S), then fill the
medication.
1 Remove the Medication
Bottle from the Main Unit.
Lift up the Medication Bottle by
pushing in the Medication Bottle
Disengaging Buttons on both sides
and releasing the engagement.
Medication Bottle
Disengaging Button
2 Remove the Mesh Cap.
Lift up the
Hold the Medication Bottle as if by
covering it with your hand.
Mesh Cap
perpendicular
to the
Medication
Bottle.
Lift up the Mesh Cap by
applying your thumb on
the brim.
Do not insert your
finger into the
Nebulization Port.
Do not open
the Bottle Cap.
3 Fill the medication.
Fill the medication as shown in the
Figure.
- The maximum capacity of
Medication Bottle is 7 ml.
Insert the Mesh Cap
perpendicular to the
Medication Bottle.
4 Install the Mesh Cap.
- If the Mesh Cap is not securely
closed, medication may leak.
Close the Mesh Cap
securely.
Align these points,
then push in as far
as it goes.
Do not insert your
finger into the
Nebulization Port.
10
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5 Install the Medication
Bottle to the Main Unit.
- If the Medication Bottle is not
installed correctly, the power will not
turn on.
Align both
Electrodes with
each other.
- If the Electrodes are extremely
stained, the unit will not nebulize
normally. In that case, wipe off the
stain.
Keep the Electrodes clean.
Installation is
complete.
6 Install the Mask Adapter.
Securely cover the
Main Unit with the
Mask Adapter.
7 Install the Inhalation Mask
or the Mouthpiece.
I How to install the Inhalation Mask (S)
I How to install the Mouthpiece
Installation is
complete.
Installation is
complete.
Insert the
Mouthpiece
as far as it
goes.
Insert the
Inhalation
Mask as far
as it goes.
11
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How to Select the Nebulization Mode
You can select the nebulization mode by the way how you push the Button.
Continuous Nebulization Mode
If you push the Button and immediately
lift your finger away from the Button
(within approximately 1 second), the unit
nebulizes in Continuous Nebulization
Mode.
Push the Button and
immediately lift your
finger (within
approximately 1
second).
If you push the Button again, the unit
stops nebulization.
Manual Nebulization Mode
If you keep pressing the Button
(approximately for 2 seconds or more), the
unit nebulizes in Manual Nebulization
Mode.
Keep on pressing
(for approximately
2 seconds or more).
The unit nebulizes only while you keep on
pressing the Button and stops nebulization
when you lift your finger from the Button.
You can inhale in tandem with respiration.
- The Power Indicator (green) turns on during nebulization.
12
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How to Inhale
1 Hold the Main Unit with
your hand and start
inhalation in relaxed
posture.
Slightly slant the Main unit (the
side of Button) towards yourself.
Medication
Immerse the Vibrator in the
medication. If the Vibrator is not
immersed such as when the Main
Unit is placed on a horizontal
surface, the unit may not nebulize.
Vibrator
- If medication or slobber collects on the Mesh, the unit stops nebulization. After
removing the Mask Adapter, Inhalation Mask, or Mouthpiece, turn off the power
once and absorb the medication or slobber with new gauze.
(If a medication has high surface activity, it may exude from Mesh holes or the
Bottle Cap, or the medication may leak from the Air Port.)
Air Port
Do not poke the Mesh or the Vibrator
with a cotton swab or a pin.
• The Mesh will be damaged and
cannot be used.
Absorb the
medication
or slobber.
- If the medication has high surface activity or viscosity such as medication
solubilizing agent or expectorant, the nebulization rate may be reduced.
- If you push the Button and starts the unit while the Vibrator is not immersed in
the medication,
(1) The Battery life may be shortened or the Battery Low Indicator may turn on.
- Slant the Main Unit and check if the Vibrator is immersed in the medication,
then push the Button and start inhalation.
- Use the unit by immersing the Vibrator of the Inhalation Port in the medication.
- Immediately after the medication is nebulized, turn off the power.
(2) A metallic sound may be generated, but it is not a trouble.
2 When you finish inhalation, push the Button to turn
off the power.
- When the optional AC Adapter is used, unplug the power plug from
the electric outlet. (Refer to Page 10.)
13
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How to Clean the Unit after Inhalation
Be sure to clean and store the unit after inhalation.
If you do not clean the unit after inhalation, medication will be dried and
adhered, and will not nebulize normally the next time. If this happens, clean the
Mesh Cap by boiling to wash off the adhered medication. (Refer to Page 16.)
1 Remove the parts from the Main Unit.
Remove Inhalation Mask or Mouthpiece, Mask Adapter, and
Medication Bottle from the Main Unit.
(Refer to Page 9.)
2 Discard the remaining medication.
After removing the Mesh Cap, open the Medication Bottle
Cap and discard the medication.
(Refer to Page 9.)
Disengage the
(1)
Medication Bottle Cap
Locking Lever and
open the Medication
Bottle Cap.
(2)
Lift up the
Mesh Cap
perpendicular
to the
Medication
Bottle.
(3)
Discard the
remaining
medication.
Do not insert your
finger into the
Nebulization Port.
Lift up the Mesh Cap by
applying your thumb on
the brim.
3 Wash the parts sufficiently in water.
Wash Inhalation Mask or Mouthpiece, Mask Adapter,
Medication Bottle, and Mesh Cap in water.
- Carefully wash the Mesh when using a medication
having high surface activity or viscosity such as
medication solubilizing agent or expectorant because
the medication is often left on the Mesh.
- Please be careful not to spray water on the Main Unit.
14
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4 Dry the parts thoroughly.
Immediately after washing the parts, wipe off water
with new gauze and dry them thoroughly.
General advice
Do not insert your
finger into the
Nebulization Port.
Never try to wipe off water with tissues
or cloth.
• Dust or lint left on the Mesh may
affect nebulization.
5 Wipe off the stain on the Main Unit.
Wipe off the stain on the Main Unit with gauze.
Keep the Electrodes clean.
If the Main Unit is heavily stained, lightly moisten gauze
with water and wipe the stain off. Then use new gauze
to wipe the Main Unit dry.
General advice
Do not wipe the Main Unit with volatile
agent such as benzene or thinner.
6 After assembling the unit, store it in
a clean place.
Immediately dry the cleaned and
disinfected parts, then store them in a
clean place.
• Miscellaneous bacteria may
propagate and may lead to
infection.
How to remove the Mesh Cover
When washing a Mesh
cap, you can remove
the Mesh Cap Cover
as shown in the Figure.
- Do not insert your
finger into the Mesh
Cap.
- Be sure to install
the Mesh Cap
Cover to the Mesh
Cap after cleaning.
Do not insert your
finger into the
Nebulization Port.
15
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How to Disinfect
This unit can be easily cleaned and disinfected because the Medication Bottle
and the Mesh Cap can be removed from the Main Unit.
The unit can be disinfected with benzalkonium chloride.
- Disinfection at the medical facility for medical treatment must be done after
confirming the target bacteria and the effects of disinfection method.
1 Make a 0.1% diluted solution using benzalkonium
chloride, such as Osvan S and soak the unit for 10
minutes.
- As for the dilution method, follow the instruction manual of benzalkonium
chloride.
- Do not leave the unit soaked in the solution for a long time.
2 Remove the unit from the solution and rinse it with water.
3 Immediately dry the unit by wiping off water with new
gauze.
Do not disinfect the unit with the
disinfection solution containing
sodium hypochlorite.
• The unit may not be able to be
used after getting covewred with
rust.
The following parts can be cleaned by boiling.
Mesh Cap, Inhalation Mask, Mouthpiece, Mask Adapter
(1) Place the parts in a container filled with sufficient water, and bring to boil.
(2) The parts can be disinfected by boiling for 10 to 30 minutes.
(3) When disinfection is finished, immediately dry the parts by
wiping thoroughly with new gauze.
- Never dry the parts in the microwave oven.
- Never wipe dry with tissues or cloth. Dust or lint left on the
Mesh may affect nebulization.
Parts that cannot be disinfected by boiling
Medication Bottle, Main Unit, Main Unit Cover,
Battery Cover, AC Adapter, Storage Bag
16
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How to Replace the Mash Cap
You can usually use a Mesh Cap for approximately 1 year (according to the test result of
OMRON). However, the unit may not nebulize even before using it a year depending on
how you use it. The unit also may not nebulize or nebulize extremely weak even after
disinfected by boiling. In those cases, replace the Mesh Cap with a new one.
(Mesh Cap is a consumable part.)
For the inquiry on where to purchase the Mesh Cap or the broken or lost accessory,
contact the store where you purchased the unit or the nearest OMRON dealer.
1 Remove the Medication
Bottle from the Main Unit.
- Lift up the Medication Bottle from
the Main Unit by pushing in the
Medication Bottle Disengaging
Buttons from both sides and
releasing the engagement.
Medication Bottle
Disengaging Button
2 Remove the Mesh Cap
from the Medication Bottle
Lift up the
Mesh Cap
perpendicular
to the
Medication
Bottle.
Do not insert your
finger into the
Nebulization Port.
Lift up the Mesh Cap by
applying your thumb on
the brim.
Insert the Mesh Cap
perpendicular to the
Medication Bottle.
3 Install a new Mesh Cap.
- The nebulization rate may vary
depending on the type of Mesh
Cap you use.
Close the Mesh Cap
securely.
Align these points,
then push in as far
as it goes.
Do not insert your
finger into the
Nebulization Port.
17
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How to Carry the Unit
You can carry the with the Mouthpiece or
the Inhalation Mask in the Storage Bag.
- When carrying the unit, cover the Main
Unit with a Main Unit Cover.
- Wash the storage bag when it becomes
dirty.
- Do not place the AC Adapter in the
storage bag to avoid the Main Unit
being scratched.
For Optional AC adapter:
Bundle the power cord of AC Adapter and
bind it with the AC Adapter using a Cord
Band as shown in the Figure.
Cord band
General advice
Do not leave or carry the unit containing
residual medication or water in the
Medication Bottle.
• Medication may leak and damage the
Main Unit or stain the area around
the unit.
Do not place the unit under high
temperature, high humidity, and direct
sunshine.
18
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Troubleshooting
If any trouble occurs while you are using the unit, please check the following first.
Trouble
Possible cause
How to correct
The Battery Low Indicator
flashes / turns on, and the
batteries are low/worn out.
Replace the batteries with new ones.
(Refer to page 9.)
The
nebulization
rate is
Clean the Mesh Cap by boiling to
remove the stain. (Refer to Page 16.)
- If the trouble cannot be corrected by
the above-mentioned procedure,
replace the Mesh Cap with a new
extremely low.
The Mesh is stained.
one.
(Refer to Page 17.)
Insert batteries in the correct
alignment.
(Refer to Page 9.)
Replace batteries with new ones.
(Refer to Page 9.)
The polarities (+ and -) of batteries
are in the wrong direction.
The batteries are low.
The Power
The capacity of rechargeable
batteries (nickel-hydrogen
batteries) is low.
Recharge the batteries with a
commercially available recharger or
replace them with new ones.
Indicator does
not turn on and
the unit does
not nebulize.
The AC Adapter is not correctly
connected to the electric outlet
of the Connection Port of Main
Unit.
Remove the AC Adapter from the
Main Unit and connect it correctly.
(Refer to Page 8.)
The Medication Bottle is not
installed correctly to the Main Unit.
Install the Medication Bottle correctly.
(Refer to Page 11.)
The Medication Bottle is not
filled with medication.
Fill the medication.
(Refer to Page 10.)
Clean the Mesh Cap by boiling to
remove the stain. (Refer to Page 16.)
- If the trouble cannot be corrected by
the above-mentioned procedure,
replace the Mesh Cap with a new
The Mesh is extremely stained.
one.
Replace the Mesh Cap with a new
one. (Refer to Page 17.)
(Refer to Page 17.)
The Power
Indicator turns
on but the unit
does not
The Mesh is broken.
Medication is not supplied to the Use the unit by slightly slanting the
Medication Bottle. (Medication is Main Unit (the side of the Button)
not in contact with the Vibrator.) towards yourself. (Refer to Page 13.)
nebulize.
Medication or water is collected
Remove the medication or water.
on the Electrodes of the Main
(Refer to Page 13.)
Unit.
The Electrode of the Main Unit
Wipe off the stain. (Refer to Page 15.)
is stained.
If the unit does not nebulize normally after taking the above-mentioned procedure, contact the store
where you purchased the unit or the nearest OMRON dealer.
19
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Specifications
Product name:
Model:
Omron Mesh Nebulizer
NE-U22
Power source:
3 VDC (two AA alkaline batteries)
2.4 VDC (two AA nickel-hydrogen batteries)
optional AC adapter
Power consumption:
Ultrasonic frequency:
Nebulization rate:
Particle size:
Approximately 1.5 W*
Approximately 180 kHz
0.25 ml / minute or more*
MMAD approximately 5 µm (Measured by OMRON based on
CEN/TC215)
Capacity of
Medication Bottle:
Maximum of 7 ml
External dimensions:
Weight:
Approximately 38 (W) x 104 (H) x 51 (D) mm
Approximately 97 g (not including batteries)
Battery life:
Approximately 4 hours* with continuous nebulization
Approximately 8 days when used about 30 minutes a day
(with the use of alkaline batteries)
Operating temperature
and humidity:
10 to 40°C, 30 to 85% RH
Accessories:
Inhalation Mask (S), Inhalation Mask (L), Mouthpiece, Mask
Adapter, Storage Bag, Instruction Manual
* Under normal temperature of 23°C. When nebulizing physiological saline. (Varies with the type of
medication.)
- Nebulization rate is lowered at low temperature.
- The unit turns off automatically in approximately 30 minutes after the power is turned on.
- Specifications and appearance may be changed without prior notice for improvement.
Option Parts
Parts that can be purchased separately
U10-1-P: Inhalation
Mask (L) (with a
rubber string)
U10-2-P: Inhalation
Mask (S) (with a
rubber string)
U22-1: Mouthpiece
U22-2: Mask Adapter
U22-7: Storage Bag
U22-3: Medication
Bottle
U22-4: Mesh Cap
(With a mesh)
U22-5: AC Adapter
For the inquiry on where to purchase the option parts, contact the
store where you purchased the unit or the nearest OMRON dealer.
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